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牙科工作人员的尿汞水平及相关症状

Urine mercury levels and associated symptoms in dental personnel.

作者信息

Nilsson B, Gerhardsson L, Nordberg G F

机构信息

Department of Environmental Medicine, University of Umeå, Sweden.

出版信息

Sci Total Environ. 1990 May 15;94(3):179-85. doi: 10.1016/0048-9697(90)90169-u.

Abstract

Dental personnel are exposed to low concentrations of mercury vapor in their working environment and from their own amalgam fillings. This study included 505 occupationally exposed individuals working at 82 dental clinics in northern Sweden and 41 controls without occupational mercury exposure. The concentration of mercury in air was measured. Urine mercury was determined for all participants, who also answered a questionnaire focused on four symptoms known from the literature to be connected with mercury exposure, namely loss of appetite, tremor, insomnia and anxiety. The median value of mercury vapor in air in the dental surgeries was low compared with other investigations; 1.5 micrograms m-3 in public dental care and 3.6 micrograms m-3 in private dental care. The urine mercury concentrations (HgU) were low, and of the same order of magnitude as for the Swedish population as a whole. Median values among different groups of dental personnel ranged from 1.4 to 2.9 nmol Hg/mmol creatinine. For those occupationally exposed, the load from their own amalgam fillings was estimated to be of the same order of magnitude as from the working environment. The prevalence of any of the four symptoms investigated in the groups of exposed personnel and controls as low, less than or equal to 11%. In our study, which included mercury intakes up to twice the contribution from amalgam fillings, no increase in the prevalence of symptoms could be detected in relation to mercury concentrations in urine.

摘要

牙科工作人员在其工作环境中以及自身的汞合金填充物中会接触到低浓度的汞蒸气。本研究纳入了瑞典北部82家牙科诊所的505名职业接触汞的个体以及41名无职业汞接触的对照人员。测量了空气中汞的浓度。测定了所有参与者的尿汞含量,他们还回答了一份问卷,该问卷聚焦于文献中已知的与汞接触相关的四种症状,即食欲不振、震颤、失眠和焦虑。与其他调查相比,牙科手术室内空气中汞蒸气的中位数较低;公共牙科保健机构中为1.5微克/立方米,私人牙科保健机构中为3.6微克/立方米。尿汞浓度(HgU)较低,与瑞典总体人群处于同一数量级。不同组别的牙科工作人员的中位数在1.4至2.9纳摩尔汞/毫摩尔肌酐之间。对于那些职业接触汞的人员,其自身汞合金填充物带来的汞负荷估计与工作环境带来的汞负荷处于同一数量级。在接触汞的人员组和对照组中,所调查的四种症状中任何一种的患病率都很低,小于或等于11%。在我们的研究中,汞摄入量高达汞合金填充物贡献量的两倍,但未发现症状患病率与尿汞浓度之间存在增加的关系。

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