Abia Wilfred Angie, Simo Grace Nella, Warth Benedikt, Sulyok Michael, Krska Rudolf, Tchana Angele, Moundipa Paul Fewou
Laboratory of Pharmacology and Toxicology, Department of Biochemistry, Faculty of Science, University of Yaounde I, P.O. Box 812, Yaounde, Cameroon.
Jpn J Vet Res. 2013 Feb;61 Suppl:S33-9.
For the first time in Cameroon, this paper reports on multiple mycotoxins occurrences in poultry feeds. Twenty feed samples collected from different poultry farms were analyzed for 320 fungal metabolites by liquid chromatography electrospray ionization tandem mass spectrometry. Results showed feeds contamination by 68 metabolites including 18 mycotoxins/metabolites currently regulated in the European Union such as fumonisins B1 (FB1), B2, and B3; deoxynevalenol (DON); and beta-zearalenol recovered in all samples. FB1 reported highest FB mean level of 468 (range 16-1930) microg kg(-1). Levels of DON and ZEN were mostly concentrated in feeds from western-highlands conversely for FBs and aflatoxins concentrations in Yaounde. Aflatoxin B1 mean level of 40 microg kg(-1) exceeded the worldwide permitted limit for aflatoxins in feed and generally inversely proportional to weight gain in chicken.
本文首次报道了喀麦隆家禽饲料中多种霉菌毒素的存在情况。通过液相色谱电喷雾电离串联质谱法，对从不同家禽养殖场采集的20份饲料样本进行了320种真菌代谢物的分析。结果显示，饲料受到68种代谢物的污染，其中包括18种目前在欧盟受到监管的霉菌毒素/代谢物，如伏马菌素B1（FB1）、B2和B3；脱氧雪腐镰刀菌烯醇（DON）；以及在所有样本中均检测到的β-玉米赤霉烯醇。FB1的平均含量最高，为468（范围为16 - 1930）微克/千克（-1）。DON和ZEN的含量大多集中在西部高地的饲料中，而雅温得的饲料中FBs和黄曲霉毒素的浓度则相反。黄曲霉毒素B1的平均含量为40微克/千克（-1），超过了全球饲料中黄曲霉毒素的允许限量，并且通常与鸡的体重增加成反比。
