Servicio de Protección Radiológica y Radiofísica Hospitalaria, Hospital Infanta Cristina, 06080 Badajoz, Spain.
Med Phys. 2013 May;40(5):051712. doi: 10.1118/1.4801902.
Megavoltage grid therapy is currently delivered with step-and-shoot multisegment techniques or using a high attenuation block with divergent holes. However, the commercial availability of grid blocks is limited, their construction is difficult, and step-and-shoot techniques require longer treatment times and are not practical with some multileaf collimators. This work studies the feasibility of a hybrid collimation system for grid therapy that does not require multiple segments and can be easily implemented with widely available technical means.
The authors have developed a system to generate a grid of beamlets by the simultaneous use of two perpendicular sets of equally spaced leaves that project stripe patterns in orthogonal directions. One of them is generated with the multileaf collimator integrated in the accelerator and the other with an in-house made collimator constructed with a low melting point alloy commonly available at radiation oncology departments. The characteristics of the grid fields for 6 and 18 MV have been studied with a shielded diode, an unshielded diode, and radiochromic film.
The grid obtained with the hybrid collimation is similar to some of the grids used clinically with respect to the beamlet size (about 1 cm) and the percentage of open beam (1/4 of the total field). The grid fields are less penetrating than the open fields of the same energy. Depending on the depth and the direction of the profiles (diagonal or along the principal axes), the measured valley-to-peak dose ratios range from 5% to 16% for 6 MV and from 9% to 20% for 18 MV. All the detectors yield similar results in the measurement of profiles and percent depth dose, but the shielded diode seems to overestimate the output factors.
The combination of two stripe pattern collimators in orthogonal directions is a feasible method to obtain two-dimensional arrays of beamlets and has potential usefulness as an efficient way to deliver grid therapy. The implementation of this method is technically simpler than the construction of a conventional grid block.
目前,兆伏级网格治疗是通过步进式多段技术或使用带有发散孔的高衰减块来实现的。然而,商业上可获得的网格块数量有限,其构造困难,步进式技术需要更长的治疗时间,并且不适用于某些多叶准直器。这项工作研究了一种不需要多个段且可以用广泛可用的技术手段轻松实现的混合准直系统用于网格治疗的可行性。
作者开发了一种系统,通过同时使用两组等间距的叶片来产生射束束流的网格,这些叶片在正交方向上投射条纹图案。其中一组由集成在加速器中的多叶准直器生成,另一组由使用在放射肿瘤学部门中常用的低熔点合金制成的自制准直器生成。使用屏蔽二极管、非屏蔽二极管和光致变色胶片研究了 6MV 和 18MV 的网格场特性。
混合准直获得的网格在束流大小(约 1cm)和开放束的百分比(总场的 1/4)方面与临床上使用的一些网格相似。与相同能量的开放场相比,网格场的穿透性较差。根据深度和轮廓的方向(对角线或沿主轴线),测量的谷峰剂量比范围为 6MV 时为 5%至 16%,18MV 时为 9%至 20%。所有探测器在测量轮廓和百分深度剂量时都产生相似的结果,但屏蔽二极管似乎高估了输出因子。
两个条纹图案准直器在正交方向上的组合是获得二维束流阵列的可行方法,并且作为一种有效的网格治疗方法具有潜在的用途。这种方法的实施在技术上比构建传统的网格块更简单。