Olivares-Hernandez Ana Elisabeth, Olivares-Robles Miguel Angel, Méndez-Méndez Juan Vicente, Gutiérrez-Camacho Claudia
Instituto Politecnico Nacional, Seccion de Estudios de Posgrado e Investigacion, Escuela Nacional de Ciencias Biologicas, Ciudad de Mexico 11340, Mexico.
Instituto Politecnico Nacional, Seccion de Estudios de Posgrado e Investigacion, Escuela Superior de Ingenieria Mecanica y Electrica Unidad Culhuacan, Coyoacan, Ciudad de Mexico 04430, Mexico.
J Funct Biomater. 2024 Sep 25;15(10):283. doi: 10.3390/jfb15100283.
Wear on the surface of the femoral head increases the risk of hip and femur fractures. Biomechanical experiments conducted on the femur are based on its bending and torsional rigidities. Studies regarding the deflection of the femur bone when the femoral head is coated with microfilms composed of durable and compatible biomaterials are poor. This study aimed to investigate the effects of different biomaterial microfilm coatings over the femoral head on the deflection of the human femur. We utilized 2023 R1 finite element analysis (FEA) software to model the directional deformation on the femoral head and examine the femur's deflection with varying microfilm thicknesses. The deflection of the femur bone was reported when the femoral head was uncoated and coated with titanium, stainless steel, and pure gold microfilms of different thicknesses (namely, 50, 75, and 100 μm). Our results show that the femur's minimum and maximum deflection occurred for stainless steel and gold, respectively. The deformation of the femur was lower when the femoral head was coated with a 50-micrometer microfilm of stainless steel, compared to the deformation obtained with gold and titanium. When the thickness of the microfilm for each of the materials was increased, the deformation continued to decrease. The minimum deformation of the femur occurred for a thickness of 100 μm with stainless steel, followed by titanium and gold. The difference in the directional deformation of the femur between the materials was more significant when the coating was 100 μm, compared to the thicknesses of 50 and 75 μm. The findings of this study are expected to significantly contribute to the development of advanced medical techniques to enhance the quality of life for patients with femur bone-related issues. This information can be used to develop more resilient coatings that can withstand wear and tear.
股骨头表面的磨损会增加髋部和股骨骨折的风险。对股骨进行的生物力学实验是基于其弯曲和扭转刚度。关于在股骨头涂覆由耐用且兼容的生物材料组成的微薄膜时股骨的挠度的研究很少。本研究旨在调查股骨头表面不同生物材料微薄膜涂层对人体股骨挠度的影响。我们使用2023 R1有限元分析（FEA）软件对股骨头的定向变形进行建模，并研究不同微薄膜厚度下股骨的挠度。报告了股骨头未涂层以及涂覆不同厚度（即50、75和100μm）的钛、不锈钢和纯金微薄膜时股骨的挠度。我们的结果表明，股骨的最小和最大挠度分别出现在不锈钢和金涂层的情况下。与金和钛涂层相比，当股骨头涂覆50微米厚的不锈钢微薄膜时，股骨的变形较小。当每种材料的微薄膜厚度增加时，变形继续减小。股骨的最小变形出现在不锈钢涂层厚度为100μm时，其次是钛涂层和金涂层。与50μm和75μm的厚度相比，当涂层为100μm时，不同材料之间股骨的定向变形差异更为显著。本研究的结果有望为先进医疗技术的发展做出重大贡献，以提高患有股骨相关问题患者的生活质量。这些信息可用于开发更具弹性、能够承受磨损的涂层。
