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临床药理学在日常临床护理中的应用。

Clinical pharmacology in everyday clinical care.

机构信息

Philipp Klee-Institute of Clinical Pharmacology, HELIOS Klinikum Wuppertal, University of Witten/Herdecke, Heusnerstrasse 40, 42283 Wuppertal, Germany.

出版信息

Eur J Clin Pharmacol. 2013 May;69 Suppl 1:89-93. doi: 10.1007/s00228-013-1490-z. Epub 2013 May 3.

Abstract

Since direct patient care is only one of the many fields of clinical pharmacologists world wide, the contribution of the discipline to the provision of healthcare is frequently underestimated. Besides therapeutic monitoring and pharmacogenetic services, particularly drug information services run by clinical pharmacology departments have been established in many countries. Despite the fact that electronic prescribing support may prevent physicians from major medication errors due to drug-drug interactions and inadequate dosages, a substantial number of questions addressed to drug information services include clinical expertise and judgement. Furthermore, a high number of requests deal with adverse drug interactions and involve requests for alternative drugs in the individual clinical context. Using information technology, an international web-based clinical pharmacology service using existing knowledge databases seems to be a promising option to demonstrate the excellence of the discipline.

摘要

由于直接的患者护理只是全球临床药理学家众多领域之一,因此该学科对医疗保健的贡献经常被低估。除了治疗监测和药物遗传学服务外,许多国家还建立了临床药理学部门提供的特别药物信息服务。尽管电子处方支持可能会因为药物相互作用和剂量不足而防止医生犯重大用药错误,但向药物信息服务提出的大量问题包括临床专业知识和判断。此外,大量请求涉及药物不良反应相互作用,并涉及在个体临床情况下请求替代药物。利用信息技术,使用现有知识库的国际基于网络的临床药理学服务似乎是展示该学科卓越表现的一个有前途的选择。

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