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本文引用的文献

1
N-Heterocyclic Carbene Bound Nickel(I) Complexes and Their Roles in Catalysis.氮杂环卡宾配位的镍（I）配合物及其在催化中的作用。
Organometallics. 2011 May 9;30(9):2546-2552. doi: 10.1021/om200090d.
2
Nickel-catalyzed Kumada cross-coupling reactions of tertiary alkylmagnesium halides and aryl bromides/triflates.镍催化的三级烷基卤代镁和芳基溴化物/三氟甲磺酸酯的 Kumada 交叉偶联反应。
J Am Chem Soc. 2011 Jun 8;133(22):8478-81. doi: 10.1021/ja202769t. Epub 2011 May 12.
3
Nickel-catalyzed cross-coupling of aryl bromides with tertiary Grignard reagents utilizing donor-functionalized N-heterocyclic carbenes (NHCs).利用供体官能化的N-杂环卡宾（NHCs）实现镍催化芳基溴化物与叔格氏试剂的交叉偶联反应。
Chemistry. 2011 May 23;17(22):6052-5. doi: 10.1002/chem.201100909. Epub 2011 Apr 20.
4
Highly diastereoselective C(sp3)-C(sp) cross-coupling reactions between 1,3- and 1,4-substituted cyclohexylzinc reagents and bromoalkynes through remote stereocontrol.通过远程立体控制实现1,3-和1,4-取代的环己基锌试剂与溴代炔烃之间的高度非对映选择性C(sp3)-C(sp)交叉偶联反应。
Angew Chem Int Ed Engl. 2011 Feb 25;50(9):2174-7. doi: 10.1002/anie.201006879. Epub 2011 Feb 1.
5
Advances in transition metal (Pd, Ni, Fe)-catalyzed cross-coupling reactions using alkyl-organometallics as reaction partners.以烷基有机金属化合物作为反应伙伴的过渡金属（钯、镍、铁）催化交叉偶联反应的进展。
Chem Rev. 2011 Mar 9;111(3):1417-92. doi: 10.1021/cr100327p. Epub 2011 Feb 14.
6
Nickel-catalyzed Negishi cross-coupling reactions of secondary alkylzinc halides and aryl iodides.镍催化的仲烷基卤化锌与芳基碘的 Negishi 交叉偶联反应。
Org Lett. 2011 Mar 4;13(5):1218-21. doi: 10.1021/ol200098d. Epub 2011 Feb 10.
7
Negishi cross-coupling of secondary alkylzinc halides with aryl/heteroaryl halides using Pd-PEPPSI-IPent.使用 Pd-PEPPSI-IPent 实现仲烷基卤化物与芳基/杂芳基卤化物的 Negishi 交叉偶联。
Chem Commun (Camb). 2011 May 14;47(18):5181-3. doi: 10.1039/c0cc04835f. Epub 2011 Feb 1.
8
Alternative mechanistic explanation for ligand-dependent selectivities in copper-catalyzed N- and O-arylation reactions.铜催化的 N-和 O-芳基化反应中配体依赖性选择性的另一种机制解释。
J Am Chem Soc. 2010 Dec 29;132(51):18078-91. doi: 10.1021/ja104264v. Epub 2010 Dec 6.
9
Highly diastereoselective Csp₃-Csp₂ Negishi cross-coupling with 1,2-, 1,3- and 1,4-substituted cycloalkylzinc compounds.高非对映选择性 Csp₃-Csp₂ Negishi 交叉偶联与 1,2-、1,3-和 1,4-取代的环烷基锌化合物。
Nat Chem. 2010 Feb;2(2):125-30. doi: 10.1038/nchem.505. Epub 2010 Jan 17.
10
Stereospecific cross-coupling of secondary alkyl β-trifluoroboratoamides.立体选择性交叉偶联仲烷基 β-三氟硼酰胺。
J Am Chem Soc. 2010 Dec 8;132(48):17108-10. doi: 10.1021/ja108949w. Epub 2010 Nov 15.

叔烷基镁亲核试剂在镍催化交叉偶联反应中的应用

The Use of Tertiary Alkylmagnesium Nucleophiles in Ni-Catalyzed Cross-Coupling Reactions.

作者信息

Joshi-Pangu Amruta, Biscoe Mark R

机构信息

Department of Chemistry, The City College of New York, 160 Convent Avenue, New York, NY 10031, USA.

出版信息

Synlett. 2012 May 14;23(8):1103-1107. doi: 10.1055/s-0031-1290765.

DOI:10.1055/s-0031-1290765
PMID:23641126
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3639446/
Abstract

Nickel-catalyzed cross-coupling reactions of unactivated tertiary alkyl nucleophiles and aryl bromides have been developed using -heterocyclic carbene ligands. These processes are reviewed alongside earlier attempts to employ unactivated tertiary alkyl nucleophiles in cross-coupling reactions. Potential mechanisms for the transformations, and future challenges in this field are discussed.

摘要

利用N-杂环卡宾配体，已开发出镍催化的未活化叔烷基亲核试剂与芳基溴的交叉偶联反应。本文在回顾早期在交叉偶联反应中使用未活化叔烷基亲核试剂尝试的同时，对这些反应过程进行了综述。讨论了这些转化反应的潜在机理以及该领域未来面临的挑战。