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荧光在机器人普通外科手术中的应用:文献综述与现状

Application of fluorescence in robotic general surgery: review of the literature and state of the art.

作者信息

Marano Alessandra, Priora Fabio, Lenti Luca Matteo, Ravazzoni Ferruccio, Quarati Raoul, Spinoglio Giuseppe

机构信息

Department of General and Oncologic Surgery, SS Antonio e Biagio Hospital, Via Venezia 16, 15121, Alessandria, Italy,

出版信息

World J Surg. 2013 Dec;37(12):2800-11. doi: 10.1007/s00268-013-2066-x.

DOI:10.1007/s00268-013-2066-x
PMID:23645129
Abstract

The initial use of the indocyanine green fluorescence imaging system was for sentinel lymph node biopsy in patients with breast or colorectal cancer. Since then, application of this method has received wide acceptance in various fields of surgical oncology, and it has become a valid diagnostic tool for guiding cancer treatment. It has also been employed in numerous conventional surgical procedures with much success and benefit to the patient. The advent of minimally invasive surgery brought with it a new use for fluorescence in helping to improve the safety of these procedures, particularly for single-site procedures. In 2010, a near-infrared camera was integrated into the da Vinci Si System, creating a combination of technical and minimally invasive advantages that have been embraced by several experienced surgeons. The use of fluorescence, although useful, is considered challenging. Only a few studies are currently available on the use of fluorescence in robotic general surgery, whereas many articles have focused on its application in open and laparoscopic surgery. Many of these reports describe promising and satisfactory results, although with some shortcomings. The purpose of this article is to review the current status of the use of fluorescence in general surgery and particularly its role in robotic surgery. We also review potential uses in the future.

摘要

吲哚菁绿荧光成像系统最初用于乳腺癌或结直肠癌患者的前哨淋巴结活检。从那时起,该方法在外科肿瘤学的各个领域得到了广泛认可,并已成为指导癌症治疗的有效诊断工具。它还被应用于众多传统外科手术中,取得了巨大成功,并给患者带来了益处。微创手术的出现为荧光带来了新的用途,有助于提高这些手术的安全性,特别是对于单部位手术。2010年,一台近红外摄像头被集成到达芬奇Si系统中,创造了一种技术优势和微创优势相结合的方式,受到了几位经验丰富的外科医生的青睐。荧光的使用虽然有用,但也颇具挑战性。目前关于荧光在机器人普通外科手术中的应用仅有少数研究,而许多文章则聚焦于其在开放手术和腹腔镜手术中的应用。尽管存在一些缺点,但这些报告中的许多都描述了令人鼓舞和满意的结果。本文旨在综述荧光在普通外科手术中的应用现状,特别是其在机器人手术中的作用。我们还将综述其未来的潜在用途。

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本文引用的文献

1
Clinical application of fluorescence imaging of liver cancer using indocyanine green.吲哚菁绿在肝癌荧光成像中的临床应用。
Liver Cancer. 2012 Jun;1(1):15-21. doi: 10.1159/000339017.
2
Real-time near-infrared (NIR) fluorescent cholangiography in single-site robotic cholecystectomy (SSRC): a single-institutional prospective study.单部位机器人胆囊切除术(SSRC)中实时近红外(NIR)荧光胆管造影:单机构前瞻性研究。
Surg Endosc. 2013 Jun;27(6):2156-62. doi: 10.1007/s00464-012-2733-2. Epub 2012 Dec 28.
3
Fluorescence cholangiography during laparoscopic cholecystectomy: a feasibility study on early biliary tract delineation.
从器官保存到选择性手术:免疫疗法如何改变结直肠癌手术?
Surg Open Sci. 2023 Aug 9;15:44-53. doi: 10.1016/j.sopen.2023.07.024. eCollection 2023 Sep.
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Bibliometric analysis of robotic surgery research in breast cancer conducted between 2008 and 2022.2008年至2022年间乳腺癌机器人手术研究的文献计量分析。
Gland Surg. 2023 Jun 30;12(6):767-779. doi: 10.21037/gs-22-540. Epub 2023 Jun 12.
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Quantifying the Impact of Signal-to-background Ratios on Surgical Discrimination of Fluorescent Lesions.量化信号与背景比值对荧光病变手术诊断的影响。
Mol Imaging Biol. 2023 Feb;25(1):180-189. doi: 10.1007/s11307-022-01736-y. Epub 2022 Jun 16.
6
The complementary value of intraoperative fluorescence imaging and Raman spectroscopy for cancer surgery: combining the incompatibles.术中荧光成像和拉曼光谱在癌症手术中的互补价值:将不可兼容的技术结合起来。
Eur J Nucl Med Mol Imaging. 2022 Jun;49(7):2364-2376. doi: 10.1007/s00259-022-05705-z. Epub 2022 Feb 1.
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Immunofluorescence in Robotic Colon and Rectal Surgery.机器人结肠和直肠手术中的免疫荧光
Clin Colon Rectal Surg. 2021 Sep;34(5):338-344. doi: 10.1055/s-0041-1729866. Epub 2021 Sep 3.
8
Laser speckle contrast imaging and quantitative fluorescence angiography for perfusion assessment.激光散斑对比成像和定量荧光血管造影用于灌注评估。
Langenbecks Arch Surg. 2019 Jun;404(4):505-515. doi: 10.1007/s00423-019-01789-8. Epub 2019 May 4.
9
Fluorescence image-guided lymphadenectomy using indocyanine green and near infrared technology in robotic gastrectomy.在机器人胃癌根治术中使用吲哚菁绿和近红外技术的荧光图像引导下淋巴结清扫术
Chin J Cancer Res. 2018 Oct;30(5):568-570. doi: 10.21147/j.issn.1000-9604.2018.05.11.
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Chin J Integr Med. 2019 May;25(5):370-377. doi: 10.1007/s11655-018-2565-6. Epub 2018 Nov 27.
腹腔镜胆囊切除术中荧光胆管造影:早期胆道显影的可行性研究。
Surg Endosc. 2013 May;27(5):1530-6. doi: 10.1007/s00464-012-2635-3. Epub 2012 Oct 18.
4
Near-infrared fluorescence imaging can help identify the contralateral phrenic nerve during robotic thymectomy.近红外荧光成像可帮助识别机器人胸腺切除术时的对侧膈神经。
Ann Thorac Surg. 2012 Aug;94(2):622-5. doi: 10.1016/j.athoracsur.2012.04.119.
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Intra-operative fluorescent cholangiography using indocyanin green during robotic single site cholecystectomy.术中应用吲哚菁绿荧光胆管造影在机器人单部位胆囊切除术中的应用。
Int J Med Robot. 2012 Dec;8(4):436-40. doi: 10.1002/rcs.1437. Epub 2012 May 31.
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Colorectal Dis. 2013 Jan;15(1):91-6. doi: 10.1111/j.1463-1318.2012.03101.x.
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Urology. 2012 Jul;80(1):110-6. doi: 10.1016/j.urology.2012.01.076. Epub 2012 May 17.
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A review of indocyanine green fluorescent imaging in surgery.手术中吲哚菁绿荧光成像综述
Int J Biomed Imaging. 2012;2012:940585. doi: 10.1155/2012/940585. Epub 2012 Apr 22.
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Identification of the lymphatic drainage pathways from the pancreatic head guided by indocyanine green fluorescence imaging during pancreaticoduodenectomy.吲哚菁绿荧光成像引导下胰十二指肠切除术中识别胰头淋巴引流途径。
Dig Surg. 2012;29(2):132-9. doi: 10.1159/000337306. Epub 2012 Apr 24.
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Positive and negative staining of hepatic segments by use of fluorescent imaging techniques during laparoscopic hepatectomy.腹腔镜肝切除术中使用荧光成像技术对肝段进行阳性和阴性染色。
Arch Surg. 2012 Apr;147(4):393-4. doi: 10.1001/archsurg.2012.59.