• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

一名患有常见可变免疫缺陷的婴儿继发于耶氏肺孢子菌感染的肺泡蛋白沉积症。

Pulmonary alveolar proteinosis secondary to Pneumocystis jiroveci infection in an infant with common variable immunodeficiency.

作者信息

Raj Dinesh, Bhutia Tsultem Doma, Mathur Sandeep, Kabra Sushil Kumar, Lodha Rakesh

机构信息

Department of Pediatrics, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, 110029, India.

出版信息

Indian J Pediatr. 2014 Sep;81(9):929-31. doi: 10.1007/s12098-013-1027-6. Epub 2013 May 5.

DOI:10.1007/s12098-013-1027-6
PMID:23645284
Abstract

The authors report an infant with common variable immunodeficiency (CVID) with Pneumocystis pneumonia who developed secondary pulmonary alveolar proteinosis (PAP). This is the youngest infant reported to develop PAP secondary to Pneumocystis infection in an immunocompromised state. He was effectively managed with anti-microbials, frequent lung toilet, optimized mechanical ventilation, and supportive care.

摘要

作者报告了一名患有普通可变免疫缺陷(CVID)并伴有卡氏肺孢子虫肺炎的婴儿,该婴儿继发了肺泡蛋白沉积症(PAP)。这是报告中最年幼的在免疫功能低下状态下继发于卡氏肺孢子虫感染而发生PAP的婴儿。他通过使用抗菌药物、频繁肺部灌洗、优化机械通气和支持性护理得到了有效治疗。

相似文献

1
Pulmonary alveolar proteinosis secondary to Pneumocystis jiroveci infection in an infant with common variable immunodeficiency.一名患有常见可变免疫缺陷的婴儿继发于耶氏肺孢子菌感染的肺泡蛋白沉积症。
Indian J Pediatr. 2014 Sep;81(9):929-31. doi: 10.1007/s12098-013-1027-6. Epub 2013 May 5.
2
Pulmonary alveolar proteinosis associated with Pneumocystis carinii. Ultrastructural identification in bronchoalveolar lavage in AIDS and immunocompromised non-AIDS patients.与卡氏肺孢子虫相关的肺泡蛋白沉积症。艾滋病患者及免疫功能低下的非艾滋病患者支气管肺泡灌洗中的超微结构鉴定
Chest. 1990 Oct;98(4):801-5. doi: 10.1378/chest.98.4.801.
3
Herpes Simplex Virus, Cytomegalovirus, and Pneumocystis jiroveci Pneumonia in a Treatment-Naive HIV-Positive Patient with Pulmonary Alveolar Proteinosis: Case Report.一例初治的合并肺肺泡蛋白沉积症的HIV阳性患者的单纯疱疹病毒、巨细胞病毒及耶氏肺孢子菌肺炎:病例报告
J Int Assoc Provid AIDS Care. 2017 Jul/Aug;16(4):327-330. doi: 10.1177/2325957417702488. Epub 2017 Apr 10.
4
Pulmonary alveolar proteinosis.肺泡蛋白沉积症
Pathol Res Pract. 2004;200(10):693-8; discussion 699-700. doi: 10.1016/j.prp.2004.07.002.
5
Secondary pulmonary alveolar proteinosis occurring in two patients with acquired immune deficiency syndrome.两名获得性免疫缺陷综合征患者发生继发性肺泡蛋白沉积症。
Am J Med. 1986 Jun;80(6):1187-90. doi: 10.1016/0002-9343(86)90683-2.
6
[AIDS patient with pneumocystosis and pulmonary alveolar proteinosis].患有肺孢子菌病和肺泡蛋白沉积症的艾滋病患者
Pneumologia. 2009 Apr-Jun;58(2):121-4.
7
CD4+ lymphocytopenia due to common variable immunodeficiency mimicking AIDS.由于常见变异型免疫缺陷导致的CD4 +淋巴细胞减少症,酷似艾滋病。
J Clin Pathol. 1994 Apr;47(4):364-6. doi: 10.1136/jcp.47.4.364.
8
Congenital rubella pneumonitis complicated by Pneumocystis jiroveci infection with positive long term respiratory outcome: a case report and literature review.先天性风疹肺炎合并卡氏肺孢子虫感染并长期呼吸预后良好:病例报告及文献复习。
Pediatr Pulmonol. 2009 Dec;44(12):1235-9. doi: 10.1002/ppul.20980.
9
[A case of Pneumocystis jiroveci pneumonia that presented with cavity and cystic changes in a malignant thymoma patient].[1例恶性胸腺瘤患者合并耶氏肺孢子菌肺炎伴空洞和囊性改变]
Nihon Kokyuki Gakkai Zasshi. 2008 Apr;46(4):297-301.
10
[Co-infection with Mycobacterium tuberculosis and Pneumocystis jiroveci in a patient without HIV infection].[一名无HIV感染患者合并结核分枝杆菌和耶氏肺孢子菌感染]
Rev Mal Respir. 2006 Feb;23(1 Pt 1):83-7. doi: 10.1016/s0761-8425(06)71467-x.

引用本文的文献

1
Immune responses of different hosts to infection.不同宿主对感染的免疫反应。
Eur Respir Rev. 2025 Jul 9;34(177). doi: 10.1183/16000617.0247-2024. Print 2025 Jul.
2
Pulmonary Alveolar Proteinosis Due to in Type 1 Hyper-IgM Syndrome: A Case Report.1型高IgM综合征所致肺泡蛋白沉积症:一例报告
Front Pediatr. 2020 Jun 11;8:264. doi: 10.3389/fped.2020.00264. eCollection 2020.
3
Hematopoietic stem cell transplantation for pulmonary alveolar proteinosis associated with primary immunodeficiency disease.造血干细胞移植治疗与原发性免疫缺陷病相关的肺泡蛋白沉积症。

本文引用的文献

1
"A rose is a rose is a rose," but CVID is Not CVID common variable immune deficiency (CVID), what do we know in 2011?“玫瑰就是玫瑰就是玫瑰”,但 CVID 并非 CVID——普通变异型免疫缺陷(CVID),在 2011 年我们对它了解多少?
Adv Immunol. 2011;111:47-107. doi: 10.1016/B978-0-12-385991-4.00002-7.
2
Pulmonary alveolar proteinosis.肺泡蛋白沉积症。
Eur Respir Rev. 2011 Jun;20(120):98-107. doi: 10.1183/09059180.00001311.
3
Alveolar proteinosis syndrome: pathogenesis, diagnosis, and management.肺泡蛋白沉积症综合征:发病机制、诊断与治疗
Int J Hematol. 2018 May;107(5):610-614. doi: 10.1007/s12185-017-2375-1. Epub 2017 Nov 28.
4
An Emerging Role of B Cell Immunity in Susceptibility to Pneumocystis Pneumonia.B细胞免疫在肺孢子菌肺炎易感性中的新作用
Am J Respir Cell Mol Biol. 2017 Mar;56(3):279-280. doi: 10.1165/rcmb.2016-0360ED.
5
Pulmonary alveolar proteinosis: Experience from a tertiary care center and systematic review of Indian literature.肺泡蛋白沉积症:来自三级医疗中心的经验及对印度文献的系统综述
Lung India. 2016 Nov-Dec;33(6):626-634. doi: 10.4103/0970-2113.192876.
6
"Crazy-paving" pattern: A characteristic presentation of pulmonary alveolar proteinosis and a review of the literature from India.“铺路石样”表现:肺泡蛋白沉积症的一种特征性表现及来自印度的文献综述
Lung India. 2016 May-Jun;33(3):335-42. doi: 10.4103/0970-2113.180936.
7
Update on Diffuse Lung Disease in Children.儿童弥漫性肺疾病的最新进展
Chest. 2016 Mar;149(3):836-45. doi: 10.1378/chest.15-1986. Epub 2016 Jan 12.
Curr Opin Pulm Med. 2009 Sep;15(5):491-8. doi: 10.1097/MCP.0b013e32832ea51c.
4
Recurrent pulmonary alveolar proteinosis secondary to agammaglobulinemia.继发于无丙种球蛋白血症的复发性肺泡蛋白沉积症。
Pediatr Pulmonol. 2008 Jul;43(7):710-3. doi: 10.1002/ppul.20818.
5
Pulmonary alveolar proteinosis.肺泡蛋白沉积症
N Engl J Med. 1958 Jun 5;258(23):1123-42. doi: 10.1056/NEJM195806052582301.
6
Granulocyte/macrophage colony-stimulating factor-deficient mice show no major perturbation of hematopoiesis but develop a characteristic pulmonary pathology.粒细胞/巨噬细胞集落刺激因子缺陷型小鼠的造血功能未出现重大紊乱,但会发展出一种特征性的肺部病变。
Proc Natl Acad Sci U S A. 1994 Jun 7;91(12):5592-6. doi: 10.1073/pnas.91.12.5592.
7
Pulmonary alveolar proteinosis. Further evaluation of abnormal alveolar macrophages.肺泡蛋白沉积症。异常肺泡巨噬细胞的进一步评估。
Chest. 1986 Nov;90(5):656-61. doi: 10.1378/chest.90.5.656.
8
Pulmonary alveolar proteinosis associated with Pneumocystis carinii. Ultrastructural identification in bronchoalveolar lavage in AIDS and immunocompromised non-AIDS patients.与卡氏肺孢子虫相关的肺泡蛋白沉积症。艾滋病患者及免疫功能低下的非艾滋病患者支气管肺泡灌洗中的超微结构鉴定
Chest. 1990 Oct;98(4):801-5. doi: 10.1378/chest.98.4.801.
9
The lavage fluid from a patient with alveolar proteinosis inhibits the in vitro chemiluminescence response and arachidonic acid metabolism of normal guinea pig alveolar macrophages.肺泡蛋白沉积症患者的灌洗液体可抑制正常豚鼠肺泡巨噬细胞的体外化学发光反应及花生四烯酸代谢。
Am Rev Respir Dis. 1990 Nov;142(5):1068-72. doi: 10.1164/ajrccm/142.5.1068.
10
Diagnosis and management of alveolar proteinosis: the rôle of electron microscopy.肺泡蛋白沉积症的诊断与管理:电子显微镜的作用
Thorax. 1975 Apr;30(2):121-32. doi: 10.1136/thx.30.2.121.