The Institute of Vision Research, Department of Ophthalmology, Yonsei University College of Medicine, 50 Yonsei-ro, Seodaemun-gu, Seoul, 120-752, Republic of Korea.
Graefes Arch Clin Exp Ophthalmol. 2013 Sep;251(9):2163-9. doi: 10.1007/s00417-013-2356-x. Epub 2013 May 8.
To compare optical quality, ocular scattering, and higher-order aberrations (HOAs) after laser in-situ keratomileusis (LASIK) versus laser epithelial keratomileusis (LASEK).
A total of 47 eyes from 47 participants who had undergone LASIK (group I) or LASEK (group II) procedure at least 6 months prior were enrolled. Ocular aberrations and modulation transfer function (MTF) values measured using iTrace, a ray-tracing type aberrometer, were compared to MTF (modulation transfer function) cut-off values, Strehl ratio, and objective indices of scattering obtained using the Objective Quality Analysis System II (OQAS II).
There was no significant correlation between the postoperative optical quality parameters and the HOAs between both groups. In group I, the MTF cut-off value was significantly correlated with cylinder refraction (p = 0.037), and the objective scattering index (OSI) was positively correlated with spherical equivalent (p = 0.023). In group II, there was a statistically significant correlation between the OSI and achieved refractive correction (p = 0.001). Regression analysis showed that the OSI was the most significant predictor of MTF cut-off values after refractive surgery. Additionally, MTF values measured by OQAS were significantly lower than those measured by iTrace without correlation.
Optical quality after refractive surgery may be influenced by not only ocular aberrations but also by scattering. Even though the accuracies of the machines used in this study to measure optical quality have yet to be proven, this study showed limited correlation among the values measured using the two different machines after refractive surgery. Therefore, for more generalized evaluation of visual function after refractive surgery, more advanced optical devices still need to be developed.
比较 LASIK(准分子激光原位角膜磨镶术)与 LASEK(准分子激光上皮下角膜磨镶术)术后的光学质量、眼散射和高阶像差(HOA)。
共纳入 47 名至少在 6 个月前接受过 LASIK(I 组)或 LASEK(II 组)手术的患者的 47 只眼。使用 Ray-tracing 型像差仪 iTrace 测量眼像差和调制传递函数(MTF)值,并与 MTF 截止值、斯特列尔比以及使用 Objective Quality Analysis System II(OQAS II)获得的客观散射指数(OSI)进行比较。
两组之间术后光学质量参数与 HOA 之间无显著相关性。在 I 组中,MTF 截止值与柱镜屈光度显著相关(p = 0.037),客观散射指数(OSI)与等效球镜呈正相关(p = 0.023)。在 II 组中,OSI 与实际矫正屈光力呈显著相关性(p = 0.001)。回归分析显示,OSI 是屈光手术后 MTF 截止值的最显著预测因子。此外,OQAS 测量的 MTF 值明显低于 iTrace,且无相关性。
屈光手术后的光学质量可能不仅受眼像差影响,还受散射影响。尽管本研究中用于测量光学质量的两种仪器的准确性尚未得到证实,但本研究表明两种不同仪器在屈光手术后测量的数值之间相关性有限。因此,为了更全面地评估屈光手术后的视觉功能,仍需要开发更先进的光学设备。