Cui Huizhong, Zhang Ti, Yang Xinmai
KU Bioengineering Research Center, Department of Mechanical Engineering, University of Kansas, 1530 W. 15th Street, 5109 Learned Hall, Lawrence, Kansas 66045, USA.
Appl Phys Lett. 2013 Apr 1;102(13):133702. doi: 10.1063/1.4800780. Epub 2013 Apr 3.
Laser-enhanced cavitation during high intensity focused ultrasound (HIFU) was studied using a small animal model. Laser light was employed to illuminate the sample concurrently with HIFU radiation. The resulting cavitation was detected with a passive cavitation detector. The measurements were made under different combinations of HIFU treatment depths, laser wavelengths, and HIFU durations. The results demonstrated that concurrent light illumination during HIFU has the potential to enhance cavitation effect by reducing cavitation threshold .
使用小动物模型研究了高强度聚焦超声(HIFU)期间的激光增强空化效应。在HIFU辐射的同时,使用激光照射样本。用被动空化探测器检测产生的空化现象。在不同的HIFU治疗深度、激光波长和HIFU持续时间组合下进行测量。结果表明,HIFU期间的同步光照有可能通过降低空化阈值来增强空化效应。