儿童过敏性紫癜：120例临床分析
Henoch Schonlein Purpura in children: clinical analysis of 120 cases.
作者信息
Chen O, Zhu X B, Ren P, Wang Y B, Sun R P, Wei D E
机构信息
Department of Pediatrics, Qilu Hospital, Shandong University, #107 West Wenhua Road, Jinan 250012, China.
出版信息
Afr Health Sci. 2013 Mar;13(1):94-9. doi: 10.4314/ahs.v13i1.26.
BACKGROUND
Henoch Schonlein Purpura (HSP) is a systemic vasculitic disease which is common in children. It is very important to understand the clinical features of this disease for doctors and nurses.
OBJECTIVES
To study the clinical characteristics of HSP in children.
METHODS
Collect the clinical data of the HSP children, and analyze the clinical characteristics of these HSP patients.
RESULTS
The ratio of M:F was 1.9:1. The mean age was 6.6 ± 1.6 years. The typical onset seasons were spring, winter and autumn. Infection and food allergy were the main etiological factors. The first symptom was skin purpura and these purpura mainly concentrated the lower extremities and buttocks. The dominant digestive clinical features were abdominal pains and vomiting. The knee joint and ankle joint were most frequently affected. The typical kidney symptoms were microscopic hematuria and albuminuria. An increased ESR was reported in 68 patients (56.7%). Serum C3 decreased in 13 cases (10.8%). ASO titer was higher in 57 children (47.5%).
CONCLUSION
There were gender, season and area differences for the HSP patients. The etiological factors were diverse. HSP patients could have various clinical symptoms and rare complications.
背景
过敏性紫癜（HSP）是一种常见于儿童的系统性血管炎疾病。对于医生和护士而言，了解该疾病的临床特征非常重要。
目的
研究儿童过敏性紫癜的临床特征。
方法
收集过敏性紫癜患儿的临床资料，并分析这些过敏性紫癜患者的临床特征。
结果
男女比例为1.9:1。平均年龄为6.6±1.6岁。典型的发病季节为春、冬、秋。感染和食物过敏是主要病因。首发症状为皮肤紫癜，这些紫癜主要集中在下肢和臀部。主要的消化系统临床特征为腹痛和呕吐。膝关节和踝关节最常受累。典型的肾脏症状为镜下血尿和蛋白尿。68例患者（56.7%）血沉升高。13例患者（10.8%）血清C3降低。57例儿童（47.5%）抗链球菌溶血素O滴度升高。
结论
过敏性紫癜患者存在性别、季节和地区差异。病因多样。过敏性紫癜患者可能有多种临床症状和罕见并发症。
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