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被动转移实验中特异性抗体和免疫活性细胞对肿瘤生长的影响。

Effects of specific antibodies and immunocompetent cells on tumor growth in passive transfer experiment.

作者信息

Zhigunova A V, Kravtsov E G, Yashina N V, Dalin M V, Karpenko L P

机构信息

Department of Microbiology and Virology, Russian University of Peoples' Friendship, Moscow, Russia.

出版信息

Bull Exp Biol Med. 2013 Apr;154(6):762-4. doi: 10.1007/s10517-013-2050-3.

DOI:10.1007/s10517-013-2050-3
PMID:23658918
Abstract

Experiments with passive transfer of immunocompetent cell and serum demonstrated suppression of tumor growth after transfer of splenocytes from animals immunized with Trypanosoma cruzi. The nonspecific constituent of antitumor effect of immunocompetent cells was detected. The previously reported oncoprotective effect of mucins 2 and 3 was not confirmed.

摘要

对免疫活性细胞和血清进行的被动转移实验表明,将经克氏锥虫免疫的动物的脾细胞转移后,肿瘤生长受到抑制。检测到免疫活性细胞抗肿瘤作用的非特异性成分。先前报道的粘蛋白2和3的肿瘤保护作用未得到证实。

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