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亲社会同伴关系抑制儿童期非攻击性反社会行为的遗传影响。

Prosocial peer affiliation suppresses genetic influences on non-aggressive antisocial behaviors during childhood.

作者信息

Burt S A, Klump K L

机构信息

Department of Psychology, Michigan State University, East Lansing, MI, USA.

出版信息

Psychol Med. 2014 Mar;44(4):821-30. doi: 10.1017/S0033291713000974. Epub 2013 May 10.

Abstract

BACKGROUND

Available research has suggested that affiliation with prosocial peers reduces child and adolescent antisocial behavior. However, the etiologic mechanisms driving this association remain unclear. The current study sought to evaluate whether this association takes the form of a gene-environment interaction (G × E) in which prosocial peer affiliation acts to reduce the consequences of genetic risk for non-aggressive antisocial behavior during childhood.

METHOD

Our sample consisted of 500 twin pairs aged 6-10 years from the Michigan State University Twin Registry (MSUTR).

RESULTS

The results robustly support moderation by prosocial peer affiliation. Genetic influences on non-aggressive antisocial behavior were observed to be several times larger in those with lower levels of prosocial peer affiliation than in those with higher levels of prosocial peer affiliation. This pattern of results persisted even after controlling for gene-environment correlations and deviant peer affiliation, and when restricting our analyses to those twins who shared all or nearly all of their friends.

CONCLUSIONS

Such findings not only suggest that prosocial peer affiliation moderates genetic influences on non-aggressive antisocial behaviors during childhood but also provide support for the theoretical notion that protective environmental experiences may exert their influence by promoting resilience to genetic risk.

摘要

背景

现有研究表明,与亲社会同伴交往可减少儿童和青少年的反社会行为。然而,驱动这种关联的病因机制仍不清楚。当前研究旨在评估这种关联是否采取基因-环境交互作用(G×E)的形式,即亲社会同伴交往是否能减轻童年期非攻击性反社会行为的遗传风险后果。

方法

我们的样本包括来自密歇根州立大学双胞胎登记处(MSUTR)的500对6至10岁的双胞胎。

结果

结果有力地支持了亲社会同伴交往的调节作用。研究发现,亲社会同伴交往水平较低者的遗传因素对非攻击性反社会行为的影响,比亲社会同伴交往水平较高者的影响大几倍。即使在控制了基因-环境相关性和不良同伴交往,并将分析局限于那些共享所有或几乎所有朋友的双胞胎后,这种结果模式仍然存在。

结论

这些发现不仅表明亲社会同伴交往可调节童年期遗传因素对非攻击性反社会行为的影响,还为以下理论观点提供了支持,即保护性环境体验可能通过增强对遗传风险的恢复力来发挥其影响。

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The Michigan State University Twin Registry (MSUTR): an update.密歇根州立大学双胞胎登记处(MSUTR):最新情况
Twin Res Hum Genet. 2013 Feb;16(1):344-50. doi: 10.1017/thg.2012.87. Epub 2012 Oct 29.

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