基因-环境相关性及相互作用对青少年酒精和烟草使用的同伴影响
Gene-environment correlation and interaction in peer effects on adolescent alcohol and tobacco use.
作者信息
Harden K Paige, Hill Jennifer E, Turkheimer Eric, Emery Robert E
机构信息
Department of Psychology, University of Virginia, PO Box 400400, Charlottesville, VA 22904-4400, USA.
出版信息
Behav Genet. 2008 Jul;38(4):339-47. doi: 10.1007/s10519-008-9202-7. Epub 2008 Mar 27.
Abstract
Peer relationships are commonly thought to be critical for adolescent socialization, including the development of negative health behaviors such as alcohol and tobacco use. The interplay between genetic liability and peer influences on the development of adolescent alcohol and tobacco use was examined using a nationally-representative sample of adolescent sibling pairs and their best friends. Genetic factors, some of them related to an adolescent's own substance use and some of them independent of use, were associated with increased exposure to best friends with heavy substance use--a gene-environment correlation. Moreover, adolescents who were genetically liable to substance use were more vulnerable to the adverse influences of their best friends--a gene-environment interaction.
摘要
同伴关系通常被认为对青少年社交化至关重要，包括诸如饮酒和吸烟等不良健康行为的发展。利用全国代表性的青少年同胞对及其最好朋友的样本，研究了遗传易感性与同伴影响在青少年饮酒和吸烟行为发展中的相互作用。遗传因素，其中一些与青少年自身的物质使用有关，一些与物质使用无关，与更多接触大量使用物质的最好朋友有关——这是一种基因-环境相关性。此外，在遗传上易患物质使用问题的青少年更容易受到其最好朋友的不利影响——这是一种基因-环境相互作用。
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