Department of Pathology and Veterinary Diagnostics, Faculty of Veterinary Medicine, Warsaw University of Life Sciences, Poland.
Res Vet Sci. 2013 Oct;95(2):459-64. doi: 10.1016/j.rvsc.2013.04.020. Epub 2013 May 8.
Intensive exercise and exertion during competition promote many changes that may result in the impairment of immunity and increased susceptibility to infections. The aim of this study was to evaluate the activity of "the first line of defense": neutrophils and monocytes in racing Thoroughbred and Arabian horses after routine training sessions. Twenty-three (12 Thoroughbred and 11 Arabian) horses were examined. Routine haematological (number of red blood cells - RBC, haemoglobin concentration - HGB, haematocrit - HCT, total number of white blood cells - WBC), biochemical (creatine phosphokinase activity - CPK and total protein concentration - TP) parameters, cortisol concentration as well as phagocytic and oxidative burst activity of neutrophils and monocytes were determined. The values of basic parameters and the activity of phagocytes differed between breeds and distinct patterns of exercise-induced changes were observed. The training sessions did not produce the decrease in phagocyte activity that might lead to the suppression of immunity.
剧烈运动和比赛中的用力会引起许多变化，可能导致免疫力受损和更容易感染。本研究的目的是评估“第一道防线”：在常规训练后，比赛用的纯种马和阿拉伯马的中性粒细胞和单核细胞的活性。共检查了 23 匹马（12 匹纯血马和 11 匹阿拉伯马）。常规血液学（红细胞数量 - RBC，血红蛋白浓度 - HGB，血细胞比容 - HCT，白细胞总数 - WBC）、生化（肌酸磷酸激酶活性 - CPK 和总蛋白浓度 - TP）参数、皮质醇浓度以及中性粒细胞和单核细胞的吞噬和氧化爆发活性都被确定了。基本参数的值和吞噬细胞的活性在不同品种之间存在差异，并且观察到了不同的运动诱导变化模式。训练课程并没有降低吞噬细胞的活性，这可能导致免疫力受到抑制。
