Department of Neurosurgery, First Bethune Hospital, Jilin University, Changchun, Jilin 130021, China.
Chin Med J (Engl). 2013;126(10):1934-8.
It is well recognized that meteorological factors have important infuences on the onset and development of many kinds of diseases. The present study was undertaken to investigate the effects of the meteorological elements on admission rates of cerebral infarction patients with hypertensive nephropathy at Changchun city, Jilin Province, northeast China.
A total of 763 medical records of inpatients from nine hospitals at Changchun city, during a period from April 6 to April 17 in 2010, were reviewed. These patients were admitted to hospitals due to the occurrence of cerebral infarction. The hypertensive nephropathy was evidenced with certain diagnosis of essential hypertension and hypertension-related kidney injuries. The cerebral infarction was diagnosed according to the World Health Organization (Stroke) standard. All the meteorological data were from practical monitoring records in Jilin Province Meteorological Observatory. The relationships between the epidemiological prevalence of cerebral infarction and meteorological variables were analyzed using the time series models of statistics.
Compared with admission rates before the violent change in meteorological status (April 6 to April 17, 2010), the number of admission patients suffering from cerebral infarction remarkably peaked on April 12. Such an increase was highly correlated with heavy precipitation, elevation of daily average relative humidity, and reduction of average daily air temperature. With the betterment of the meteorological conditions on April 17, the admission rates of cerebral infarction patients dropped to the same level as the dates before snowing (April 6 to April 11).
The meteorological changes are highly associated with the occurrence of cerebral infarction in patients with hypertensive renal injury in northeast China. This study also suggested that an intensive medical interference for those patients with hypertension-induced organ injuries is very necessary in preventing the occurrence of cerebral infarction with hypertensive nephropathy when there is a violent change in meteorological condition.
气象因素对许多疾病的发病和发展有重要影响，这是众所周知的。本研究旨在探讨气象要素对中国东北地区吉林省长春市高血压肾病脑梗死患者入院率的影响。
回顾 2010 年 4 月 6 日至 4 月 17 日期间长春市 9 家医院因脑梗死住院的 763 例住院病历。这些患者因脑梗死住院。高血压肾病有明确的原发性高血压和高血压相关的肾脏损伤诊断。脑梗死的诊断依据世界卫生组织（中风）标准。所有气象数据均来自吉林省气象观测站的实际监测记录。采用统计学时间序列模型分析脑梗死发病的流行病学与气象变量之间的关系。
与气象状态剧烈变化前（2010 年 4 月 6 日至 4 月 17 日）的入院率相比，4 月 12 日因脑梗死入院的患者人数明显达到高峰。这种增加与强降水、日平均相对湿度升高和平均日气温降低高度相关。随着 4 月 17 日气象条件的改善，脑梗死患者的入院率下降到与降雪前（4 月 6 日至 4 月 11 日）相同的水平。
气象变化与中国东北地区高血压肾损伤患者脑梗死的发生密切相关。本研究还表明，在气象条件剧烈变化时，对于高血压引起的器官损伤患者，有必要进行强化医疗干预，以预防高血压肾病脑梗死的发生。
