Hospital Clínic Veterinari, Universitat Autònoma de Barcelona, Bellaterra, Spain.
Vet J. 2013 Oct;198(1):43-7. doi: 10.1016/j.tvjl.2013.04.001. Epub 2013 May 14.
This review presents the consensus opinion of the Canine Leishmaniasis Working Group on the prognosis and monitoring of leishmaniasis in dogs. While the prognosis for both exposed and infected dogs is considered to be favourable, this changes if infection progresses to overt disease. For clinically affected animals undergoing treatment, the prognosis is dictated by the severity of the signs (and in particular the severity of renal dysfunction) when therapy is initiated; assessing the degree of proteinuria is useful in this context. Approximately 75% of dogs without evidence of renal involvement live for >4years if adequately treated. Monitoring the response to treatment includes ongoing clinical and clinicopathological assessment, as well as quantifying serological responses and the parasite load in the patient.
本综述介绍了犬利什曼病工作组就犬利什曼病的预后和监测达成的共识意见。虽然暴露和感染的犬的预后被认为是良好的，但如果感染进展为显性疾病，情况就会改变。对于正在接受治疗的临床受影响的动物，预后取决于治疗开始时体征的严重程度（特别是肾功能不全的严重程度）；在这种情况下，评估蛋白尿程度是有用的。如果得到充分治疗，大约 75%没有肾脏受累证据的狗可以存活超过 4 年。监测治疗反应包括持续的临床和临床病理评估，以及定量检测血清学反应和患者体内的寄生虫负荷。
