Universidade Federal do Rio Grande do Norte, UFRN, Natal, RN, Brazil.
Implant Dent. 2013 Jun;22(3):304-8. doi: 10.1097/ID.0b013e318289e311.
The aim of this study was to evaluate the literature regarding clinical efficacy and predictability of block allograft for restoration of vertical and/or horizontal bone defects.
A literature search was conducted in PubMed/MEDLINE and Cochrane databases about studies reporting the use of block allografts. The review included studies published in English from 1960 to 2011 and excluded single-case reports and articles that did not use block allograft stabilized by fixation screws.
The search revealed 567 articles, but only 14 were included, which were conducted in humans with a total of 194 patients treated with block allografts, totalizing 253 blocks.
Although a high success rate has been reported for the bone allograft survival, this systematic review demonstrated low level of scientific evidence articles with short follow-up time and diversified methodology with difficult possibilities to compare their results.
本研究旨在评估有关块状同种异体移植物用于修复垂直和/或水平骨缺损的临床疗效和可预测性的文献。
在 PubMed/MEDLINE 和 Cochrane 数据库中进行了文献检索,查找报告使用块状同种异体移植物的研究。综述包括 1960 年至 2011 年发表的英文研究,排除了单病例报告和未使用固定螺钉稳定的块状同种异体移植物的文章。
检索出 567 篇文章,但仅纳入了 14 篇,这些研究均在人类中进行,共纳入了 194 例接受块状同种异体移植物治疗的患者,共使用了 253 块移植物。
尽管同种异体骨移植的存活率报告了较高的成功率,但本系统评价显示,文献的科学证据水平较低,随访时间短,方法多样化,难以比较其结果。