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降脂药物治疗与社会经济地位:动脉粥样硬化风险社区(ARIC)监测研究。

Lipid-lowering pharmacotherapy and socioeconomic status: Atherosclerosis Risk In Communities (ARIC) surveillance study.

机构信息

Departments of Pharmacology and Biomedical Engineering, The Ohio State University Medical Center, 5072B Graves Hall 333 West 10th Avenue, Columbus, OH 43210, USA.

出版信息

BMC Public Health. 2013 May 20;13:488. doi: 10.1186/1471-2458-13-488.

Abstract

BACKGROUND

Lipid-reduction pharmacotherapy is often employed to reduce morbidity and mortality risk for patients with dyslipidemia or established cardiovascular disease. Associations between socioeconomic factors and the prescribing and use of lipid-lowering agents have been reported in several developed countries.

METHODS

We evaluated the association of census tract-level neighborhood household income (nINC) and lipid-lowering medications received during hospitalization or at discharge among 3,546 (5,335 weighted) myocardial infarction (MI) events in the United States (US) Atherosclerosis Risk In Communities (ARIC) surveillance study (1999-2002). Models included neighborhood household income, race, gender, age, study community, year of MI, hospital type (teaching vs. nonteaching), current or past history of hypertension, diabetes or heart failure, and presence of cardiac pain.

RESULTS

About fifty-nine percent of patients received lipid-lowering pharmacotherapy during hospitalization or at discharge. Low nINC was associated with a lower likelihood (prevalence ratio 0.89, 95% confidence interval: 0.79, 1.01) of receiving lipid-lowering pharmacotherapy compared to high neighborhood household income, and no significant change in this association resulted when adjusted for the above-mentioned covariates.

CONCLUSION

Patient's socioeconomic status appeared to influence whether they were prescribed a lipid-lowering pharmacotherapy after hospitalization for myocardial infarction in the US ARIC surveillance study (1999-2002).

摘要

背景

降脂药物治疗常用于降低血脂异常或已患有心血管疾病患者的发病率和死亡率风险。在一些发达国家,已经报道了社会经济因素与降脂药物的开具和使用之间的关联。

方法

我们在美国动脉粥样硬化风险社区(ARIC)监测研究(1999-2002 年)中评估了 3546 例(加权后为 5335 例)心肌梗死(MI)事件中,与人群普查区邻里家庭收入(nINC)相关的降脂药物的使用情况,包括邻里家庭收入、种族、性别、年龄、研究社区、MI 发生年份、医院类型(教学医院与非教学医院)、高血压、糖尿病或心力衰竭的现病史或既往史,以及是否存在心脏疼痛。

结果

约有 59%的患者在住院或出院期间接受了降脂药物治疗。与高邻里家庭收入相比,低 nINC 与接受降脂药物治疗的可能性较低相关(患病率比为 0.89,95%置信区间:0.79,1.01),并且在调整了上述协变量后,这种关联没有显著变化。

结论

在 ARIC 监测研究(1999-2002 年)中,患者的社会经济地位似乎影响了他们在因心肌梗死住院后是否被开具降脂药物治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6279/3663719/383e4f9f3c63/1471-2458-13-488-1.jpg

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