Department of Anaesthesia and Intensive Care, University of Foggia, Foggia, Italy.
Eur Rev Med Pharmacol Sci. 2013 May;17(9):1262-8.
Social and cultural factors combined with little information may prevent the diffusion of epidural analgesia for pain relief during childbirth. The present study was launched contemporarily to the implementation of analgesia for labor in our Department in order to perform a 2 years audit on its use. The goal is to evaluate the epidural acceptance and penetration into hospital practice by women and care givers and safety and efficacy during childbirth.
This audit cycle measured epidural analgesia performance against 4 standards: (1) Implementation of epidural analgesia for labor to all patients; (2) Acceptance and good satisfaction level reported by patients and caregivers. (3) Effectiveness of labor analgesia; (4) No maternal or fetal side effects.
During the audit period epidural analgesia increased from 15.5% of all labors in the first trimester of the study to 51% in the last trimester (p < 0.005). Satisfaction levels reported by patients and care givers were good. A hierarchical clustering analysis identified two clusters based on VAS (Visual Analogue Scale) time course: in 226 patients (cluster 1) VAS decreased from 8.5±1.4 before to 4.1±1.3 after epidural analgesia; in 1002 patients (cluster 2) VAS decreased from 8.12±1.7 before (NS vs cluster 1), to 0.76±0.79 after (p < 0.001 vs before and vs cluster 2 after). No other differences between clusters were observed.
Present audit shows that the process of implementation of labor analgesia was quick, successful and safe, notwithstanding the identification of one cluster of women with suboptimal response to epidural analgesia that need to be further studies, overall pregnant womens'adhesion to labor analgesia was satisfactory.
社会文化因素加上信息不足可能会阻碍硬膜外分娩镇痛在分娩中的普及。本研究与我们科室开始实施分娩镇痛同时进行,以便对其使用情况进行为期 2 年的审核。目的是评估产妇和医护人员对硬膜外镇痛的接受程度和在医院实践中的渗透情况,以及在分娩过程中的安全性和有效性。
该审核周期通过 4 个标准来衡量硬膜外分娩镇痛的表现:(1)对所有产妇实施硬膜外分娩镇痛;(2)产妇和照护者报告的接受度和满意度水平;(3)分娩镇痛的效果;(4)无产妇或胎儿的副作用。
在审核期间,硬膜外分娩镇痛的比例从研究初期的 15.5%增加到最后一个季度的 51%(p<0.005)。产妇和照护者报告的满意度水平较高。基于视觉模拟量表(VAS)时间进程的层次聚类分析确定了两个聚类:在 226 名患者中(聚类 1),VAS 从硬膜外镇痛前的 8.5±1.4 降至 4.1±1.3;在 1002 名患者中(聚类 2),VAS 从硬膜外镇痛前的 8.12±1.7 降至 0.76±0.79(与前相比 p<0.001,与聚类 2 后相比 p<0.001)。聚类之间没有观察到其他差异。
目前的审核表明,尽管发现了一个对硬膜外镇痛反应不佳的女性聚类,需要进一步研究,但分娩镇痛的实施过程迅速、成功且安全,总体上产妇对分娩镇痛的接受度令人满意。