Radiation Physics Department, Queen's Centre for Oncology and Haematology, Hull and East Yorkshire Hospitals NHS Trust, Castle Hill Hospital, Cottingham, UK.
Br J Radiol. 2013 Jul;86(1027):20130150. doi: 10.1259/bjr.20130150. Epub 2013 May 20.
A combination of CT and MRI is recommended for radiotherapy planning of head and neck cancers, and optimal spatial co-registration is achieved by imaging in the treatment position using the necessary immobilisation devices on both occasions, something which requires wide-bore scanners. Quality assurance experiments were carried out to commission a newly installed 1.5-T wide-bore MRI scanner and a dedicated, flexible six-channel phased array head and neck coil.
Signal-to-noise ratio (SNR) and spatial signal uniformity were quantified using a homogeneous aqueous phantom, and geometric distortion was quantified using a phantom with water-filled fiducials in a grid pattern. Volunteer scans were also used to determine the in vivo image quality. Clinically relevant T1 weighted and T2 weighted fat-suppressed sequences were assessed in multiple scan planes (both sequences fast spin echo based). The performance of two online signal uniformity correction schemes, one utilising low-resolution reference scans and the other not utilising low-resolution reference scans, was compared.
Geometric distortions, for a ±35-kHz bandwidth, were <1 mm for locations within 10 cm of the isocentre rising to 1.8 mm at 18 cm away. SNR was above 50, and uniformity in the axial plane was 71% and 95% before and after uniformity correction, respectively.
The combined performance of the wide-bore scanner and the dedicated coil was adjudged adequate, although superior-inferior spatial coverage was slightly limited in the lower neck.
These results will be of interest to the increasing number of oncology centres that are seeking to incorporate MRI into planning practice using dedicated equipment.
联合 CT 和 MRI 对头颈部癌症进行放疗规划,通过在两次治疗时都使用必要的固定装置对治疗位进行成像,实现最佳的空间配准,这需要宽孔径扫描仪。本研究进行了质量保证实验,以调试新安装的 1.5T 宽孔径 MRI 扫描仪和专用的灵活的六通道相控阵头颈部线圈。
使用均匀水模体量化信噪比(SNR)和空间信号均匀性,使用具有栅格图案的充满水基准点的水模体量化几何变形。志愿者扫描也用于确定体内图像质量。在多个扫描平面(均基于快速自旋回波序列)评估临床相关的 T1 加权和 T2 加权脂肪抑制序列。比较了两种在线信号均匀性校正方案的性能,一种利用低分辨率参考扫描,另一种不利用低分辨率参考扫描。
带宽为±35kHz 时,等中心 10cm 范围内的几何变形<1mm,18cm 处上升至 1.8mm。SNR 高于 50,轴平面的均匀性校正前为 71%,校正后为 95%。
尽管在下部颈部,上下空间覆盖范围略有受限,但宽孔径扫描仪和专用线圈的综合性能被认为是足够的。
这些结果将引起越来越多希望使用专用设备将 MRI 纳入计划实践的肿瘤学中心的兴趣。