Mandija Stefano, D'Agata Federico, Navest Robin J M, Sbrizzi Alessandro, Tijssen Rob H N, Philippens Marielle E P, Raaijmakers Cornelis P J, Seravalli Enrica, Verhoeff Joost J C, Lagendijk Jan J W, van den Berg Cornelis A T
Computational Imaging Group for MRI Diagnostics and Therapy, Center for Image Sciences, University Medical Center Utrecht, Utrecht, Netherlands.
Department of Radiotherapy, University Medical Center Utrecht, Utrecht, Netherlands.
Front Oncol. 2019 Jul 17;9:647. doi: 10.3389/fonc.2019.00647. eCollection 2019.
In brain/head-and-neck radiotherapy (RT), thermoplastic immobilization masks guarantee reproducible patient positioning in treatment position between MRI, CT, and irradiation. Since immobilization masks do not fit in the diagnostic MR head/head-and-neck coils, flexible surface coils are used for MRI imaging in clinical practice. These coils are placed around the head/neck, in contact with the immobilization masks. However, the positioning of these flexible coils is technician dependent, thus leading to poor image reproducibility. Additionally, flexible surface coils have an inferior signal-to-noise-ratio (SNR) compared to diagnostic coils. The aim of this work was to create a new immobilization setup which fits into the diagnostic MR coils in order to enhance MR image quality and reproducibility. For this purpose, a practical immobilization setup was constructed. The performances of the standard clinical and the proposed setups were compared with four tests: SNR, image quality, motion restriction, and reproducibility of inter-fraction subject positioning. The new immobilization setup resulted in 3.4 times higher SNR values on average than the standard setup, except directly below the flexible surface coils where similar SNR was observed. Overall, the image quality was superior for brain/head-and-neck images acquired with the proposed RT setup. Comparable motion restriction in feet-head/left-right directions (maximum motion ≈1 mm) and comparable inter-fraction repositioning accuracy (mean inter-fraction movement 1 ± 0.5 mm) were observed for the standard and the new setup.
在脑部/头颈部放射治疗(RT)中,热塑性固定面罩可确保患者在MRI、CT和放疗之间的治疗位置上实现可重复定位。由于固定面罩无法适配诊断性MR头部/头颈部线圈,因此在临床实践中使用柔性表面线圈进行MRI成像。这些线圈环绕头部/颈部放置,与固定面罩接触。然而,这些柔性线圈的定位依赖于技术人员,从而导致图像再现性较差。此外,与诊断性线圈相比,柔性表面线圈的信噪比(SNR)较低。这项工作的目的是创建一种新的固定装置,使其能够适配诊断性MR线圈,以提高MR图像质量和再现性。为此,构建了一种实用的固定装置。通过信噪比、图像质量、运动限制和分次间受试者定位再现性这四项测试,对标准临床固定装置和所提出的固定装置的性能进行了比较。新的固定装置平均SNR值比标准装置高3.4倍,但在柔性表面线圈正下方观察到类似的SNR值。总体而言,使用所提出的放疗固定装置获取的脑部/头颈部图像的图像质量更优。标准固定装置和新固定装置在脚到头/左右方向上具有可比的运动限制(最大运动约1毫米)和可比的分次间重新定位精度(平均分次间移动1±0.5毫米)。