Gow Alan J, Johnson Wendy, Mishra Gita, Richards Marcus, Kuh Diana, Deary Ian J
Centre for Cognitive Ageing and Cognitive Epidemiology, Department of Psychology, University of Edinburgh, Edinburgh, EH8 9JZ, UK.
Intelligence. 2012 Jan;40(1):49-59. doi: 10.1016/j.intell.2011.10.007.
Although a number of analyses have addressed whether initial cognitive ability level is associated with age-related cognitive decline, results have been inconsistent. Latent growth curve modeling was applied to two aging cohorts, extending previous analyses with a further wave of data collection, or as a more appropriate analytical methodology than used previously. In the Lothian Birth Cohort 1921, cognitive ability at age 11 was not associated with cognitive change from age 79 to 87, either in general cognitive ability, or in tests of reasoning, memory and executive function. However, data from the MRC National Survey of Health and Development suggested that higher cognitive ability at age 15 predicted less decline between ages 43 and 53 years in a latent cognitive factor from tests of verbal memory and search speed, and in search speed when considered separately. The results are discussed in terms of the differences between the cohorts and the interpretability of the analytical approach. Suggestions are made about when initial ability might be cognitively protective, and study requirements to bring about a clearer resolution.
尽管已有多项分析探讨了初始认知能力水平是否与年龄相关的认知衰退有关,但其结果并不一致。潜在增长曲线模型被应用于两个老年队列,通过进一步的数据收集浪潮扩展了先前的分析,或者作为一种比先前使用的更合适的分析方法。在1921年洛锡安出生队列中,11岁时的认知能力与79岁至87岁之间的认知变化无关,无论是一般认知能力,还是推理、记忆和执行功能测试。然而,医学研究委员会全国健康与发展调查的数据表明,15岁时较高的认知能力预示着在43岁至53岁之间,言语记忆和搜索速度测试中的潜在认知因素以及单独考虑搜索速度时的衰退较少。根据队列之间的差异和分析方法的可解释性对结果进行了讨论。就初始能力何时可能具有认知保护作用以及为实现更清晰的解决方案所需的研究要求提出了建议。