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一名血液系统恶性肿瘤患者发生头状地霉败血症,半乳甘露聚糖抗原阳性:病例报告及文献复习

Geotrichum capitatum septicemia in a hematological malignancy patient with positive galactomannan antigen: case report and review of the literature.

作者信息

Özkaya-Parlakay Aslınur, Cengiz Ali Bülent, Karadağ-Öncel Eda, Kuşkonmaz Barış, Sarıbaş Zeynep, Kara Ateş, Oğuz Berna

机构信息

Divisions of Pediatric Infectious Diseases, Hacettepe University Faculty of Medicine, Ankara, Turkey.

出版信息

Turk J Pediatr. 2012 Nov-Dec;54(6):674-8.

PMID:23692800
Abstract

Geotrichum capitatum, formerly known as Trichosporon capitatum, is an uncommon but frequently fatal invasive fungal infection in immunocompromised patients, especially in hematological malignancies. We report a seven-year-old patient with acute myeloid leukemia with Geotrichum septicemia with involvement of the lungs, liver, spleen, and kidneys, who had a favorable outcome after therapy. Alteration of antifungal treatment to liposomal amphotericin B resolved the fever with favorable clinical response.

摘要

头状地霉,以前称为头状丝孢酵母,是免疫功能低下患者中一种不常见但常致命的侵袭性真菌感染,尤其是在血液系统恶性肿瘤患者中。我们报告了一名7岁的急性髓系白血病患者,患有头状地霉败血症,累及肺、肝、脾和肾,经治疗后预后良好。将抗真菌治疗改为脂质体两性霉素B后,发热消退,临床反应良好。

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