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头状地霉侵袭性感染中半乳甘露聚糖检测:2例新病例报告及诊断方法综述

Galactomannan detection in Geotrichum capitatum invasive infections: report of 2 new cases and review of diagnostic options.

作者信息

Bonini Alessandro, Capatti Carlo, Parmeggiani Maria, Gugliotta Luigi, Micozzi Alessandra, Gentile Giuseppe, Capria Saveria, Girmenia Corrado

机构信息

Division of Hematology AO S.Maria Nuova, 42100 Reggio Emilia, University "La Sapienza", 00161 Rome, Italy.

出版信息

Diagn Microbiol Infect Dis. 2008 Dec;62(4):450-2. doi: 10.1016/j.diagmicrobio.2008.08.008. Epub 2008 Oct 21.

DOI:10.1016/j.diagmicrobio.2008.08.008
PMID:18945571
Abstract

We report 2 cases of Geotrichum capitatum infection in leukemia patients for which Aspergillus galactomannan (GM) assay was positive. The diagnostic options of G. capitatum infections in hematologic patients were reviewed. Although the pathogen was isolated from blood in 77% of cases, diagnostic difficulties remain and GM assay may have a role.

摘要

我们报告了2例白血病患者感染头状地霉的病例,其曲霉半乳甘露聚糖(GM)检测呈阳性。对血液病患者头状地霉感染的诊断选择进行了综述。尽管77%的病例中病原体是从血液中分离出来的,但诊断困难依然存在,GM检测可能会发挥作用。

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