Laboratorium für Physikalische Chemie, ETH Zürich, Zentrum, 8092 Zürich, Switzerland.
Chemphyschem. 2000 Aug 4;1(1):57-60. doi: 10.1002/1439-7641(20000804)1:1<57::AID-CPHC57>3.0.CO;2-J.
Just how different are the energies of left- and right-handed alanine enantiomers because of parity violation? Substantial advances in electroweak quantum chemistry have provided new answers to this question. The present, advanced calculations lead to the conclusion that numerous previous claims of L-alanine stabilization by parity violation are unjustified. This introduces some extra pepper into current discussions of the origin of biomolecular homochirality. The picture shows a zwitterionic model with conformational changes and solvent effects, as included in the calculations.
由于宇称破坏，左旋和右旋丙氨酸对映体的能量差异有多大？电弱量子化学的重大进展为这个问题提供了新的答案。目前先进的计算得出的结论是，之前许多关于宇称破坏导致 L-丙氨酸稳定的说法是没有根据的。这为当前关于生物分子手性起源的讨论增添了一些新的内容。图片显示了计算中包含的构象变化和溶剂效应的两性离子模型。
