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[酮替芬与变应性鼻炎患者的多导睡眠图]

[Ketotifen and polysomnography in patients with allergic rhinitis].

作者信息

Gianotti A, Franconieri N

机构信息

Centro delle Dispnee, ISMI, Università, Genova.

出版信息

G Clin Med. 1990 Apr;71(4):255-7.

PMID:2369990
Abstract

To obtain a complete study of respiratory patients, it is correct to analyze also the sleeping pattern. In these subjects, to improve respiratory tests and to reduce the bronchoconstriction, we must to use drugs with a constant action. However, during sleep, a decreased respiratory muscle function, a ventilation perfusion imbalance and a decreased response to chemical stimuli are undesirable factors related to transient desaturations. The study of sleep stages is useful to know better the respiratory disorders and the action of the drugs. We report the data of an allergic rhinitis population to evaluate the eventual modifications in sleep pattern brought upon by ketotifen.

摘要

为了全面研究呼吸系统疾病患者,分析其睡眠模式也是正确的。在这些患者中,为了改善呼吸测试结果并减轻支气管收缩,我们必须使用作用持续稳定的药物。然而,在睡眠期间,呼吸肌功能下降、通气灌注失衡以及对化学刺激的反应降低,这些都是与短暂性血氧饱和度下降相关的不良因素。研究睡眠阶段有助于更深入了解呼吸紊乱情况以及药物的作用。我们报告了一组变应性鼻炎患者的数据,以评估酮替芬对睡眠模式的最终影响。

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