Department of Medicine VI & Endocrinology, Community Medicine, Pt. BDS Post Graduate Institute of Medical Sciences, Rohtak, Haryana, India.
Indian J Med Res. 2013 Apr;137(4):728-33.
BACKGROUND & OBJECTIVES: Prevalence of gestational diabetes mellitus (GDM) is known to vary widely depending on the region of the country, dietary habits, and socio-economic status. This study was undertaken to determine the prevalence of GDM and risk factors associated with it, in women attending an antenatal care (ANC) clinic at a tertiary care hospital in Haryana.
This study enrolled women, with their estimated gestational age between 24th and 28th week, attending antenatal care (ANC) clinic at a tertiary care hospital in Rohtak. After informing, women who consented to participate were given a standardized 2-h 75 g oral glucose tolerance test (OGTT). A proforma containing general information on demographic characteristics, socio-economic status, education level, parity, family history of diabetes and/or hypertension and past history of GDM was filled up. American Diabetes Association (ADA) criteria for 75 g 2-h OGTT was used for diagnosing GDM.
A total of 607 women participated in the study and GDM was diagnosed in 43 (7.1%) women. A single abnormal value was observed in additional 66 (10.87%) women. On bivariate analysis risk factors found to be significantly associated with GDM were age, educational level, socio-economic status, pre-pregnancy weight and BMI, weight gain, acanthosis nigricans, family history of diabetes or hypertension and past history of GDM but on multivariate analysis only upper middle class and presence of acanthosis nigricans were found to be significantly associated with GDM.
INTERPRETATION & CONCLUSIONS: The prevalence of GDM was found to be 7.1 per cent in a tertiary care hospital in Haryana. Appropriate interventions are required for control and risk factor modifications.
妊娠期糖尿病(GDM)的患病率因国家/地区、饮食习惯和社会经济地位的不同而存在较大差异。本研究旨在确定印度哈里亚纳邦一家三级保健医院的产前保健(ANC)诊所就诊的女性中 GDM 的患病率及其相关的危险因素。
本研究纳入了在罗塔克的一家三级保健医院接受产前保健(ANC)的、孕龄在 24-28 周的女性。在告知参与者相关信息并获得其同意后,为其进行了标准化的 2 小时 75g 口服葡萄糖耐量试验(OGTT)。填写了一份包含一般人口统计学特征、社会经济地位、教育水平、产次、糖尿病和/或高血压家族史以及既往 GDM 病史的表格。采用美国糖尿病协会(ADA)的 75g 2 小时 OGTT 标准诊断 GDM。
共有 607 名女性参与了研究,其中 43 名(7.1%)女性被诊断为 GDM,另有 66 名(10.87%)女性出现单项异常值。在单变量分析中,与 GDM 显著相关的危险因素包括年龄、教育水平、社会经济地位、孕前体重和 BMI、体重增加、黑棘皮病、糖尿病或高血压家族史以及既往 GDM 病史,但在多变量分析中,仅中上阶层和黑棘皮病的存在与 GDM 显著相关。
在哈里亚纳邦的一家三级保健医院中,GDM 的患病率为 7.1%。需要采取适当的干预措施来控制和改变危险因素。