Chien D, Buxton R B, Kwong K K, Brady T J, Rosen B R
Department of Radiology, Beth Israel Hospital, Boston, MA.
J Comput Assist Tomogr. 1990 Jul-Aug;14(4):514-20. doi: 10.1097/00004728-199007000-00003.
Magnetic resonance diffusion imaging reflects the water mobility at each point in a tomographic image. We have studied brain water diffusion in 18 normal volunteers to identify the different factors that can influence diffusion measurements in vivo. Our results show that both the measurement accuracy and the measured diffusion coefficient strongly depend on the experimental parameters, in particular, echo and diffusion time, cardiac gating, and diffusion encoding gradient direction.
磁共振扩散成像反映断层图像中各点的水分子移动性。我们对18名正常志愿者的脑内水分子扩散进行了研究，以确定影响体内扩散测量的不同因素。我们的结果表明，测量准确性和测得的扩散系数都强烈依赖于实验参数，尤其是回波时间、扩散时间、心脏门控以及扩散编码梯度方向。
