Henninger Michelle, Crane Bradley, Naleway Allison
Senior Research Associate at The Center for Health Research in Portland, OR, USA.
Perm J. 2013 Spring;17(2):31-6. doi: 10.7812/TPP/12-115.
Pregnant women are at increased risk of severe influenza-related complications and hospitalizations and are a priority group for influenza vaccination.
To examine coverage of seasonal and pandemic influenza A (H1N1) vaccines in pregnant women in a managed care setting, from 2008 to 2012.
Retrospective cohort study of 10,145 pregnant women.
H1N1 and seasonal influenza vaccination rates.
Seasonal influenza vaccine coverage increased from 38% to 63% between the 2008-2009 and 2010-2011 seasons, and then dropped to 61% in 2011-2012. Vaccine coverage was higher in women considered at high risk of influenza complications, increasing from 43% in 2008-2009 to 71% in 2010-2011, before decreasing to 69% in 2011-2012. H1N1 vaccine coverage was greater than seasonal influenza coverage in 2009-2010 in the overall pregnant population (61% vs 53%) and in the high-risk group (64% vs 59%). We observed statistically significant differences in vaccination rates by trimester, gravidity, maternal age, and race/ethnicity.
Vaccination rates increased significantly from 2008 to 2011, then dropped slightly in 2011-2012. Continued efforts are needed to ensure adequate vaccination coverage in this high-risk population.
孕妇患严重流感相关并发症和住院的风险增加,是流感疫苗接种的重点人群。
研究2008年至2012年在管理式医疗环境中孕妇接种季节性流感疫苗和甲型H1N1流感大流行疫苗的覆盖率。
对10145名孕妇进行回顾性队列研究。
甲型H1N1流感和季节性流感疫苗接种率。
2008 - 2009年至2010 - 2011年期间,季节性流感疫苗覆盖率从38%升至63%,然后在2011 - 2012年降至61%。被认为患流感并发症高危的女性疫苗覆盖率更高,从2008 - 2009年的43%增至2010 - 2011年的71%,之后在2011 - 2012年降至69%。在2009 - 2010年,总体孕妇人群(61%对53%)和高危组(64%对59%)中,甲型H1N1流感疫苗覆盖率高于季节性流感疫苗覆盖率。我们观察到不同孕期、妊娠次数、产妇年龄和种族/族裔的疫苗接种率存在统计学显著差异。
2008年至2011年疫苗接种率显著上升,然后在2011 - 2012年略有下降。需要持续努力以确保这一高危人群有足够的疫苗接种覆盖率。