Laboratório de Reatividade Cardiovascular, Setor de Fisiologia e Farmacologia, Instituto de Ciências Biológicas e da Saúde, Universidade Federal de Alagoas, Maceió, Alagoas, Brazil.
J Rehabil Med. 2013 Jun;45(6):572-9. doi: 10.2340/16501977-1148.
To evaluate the impact of a short-term cardiovascular physical programme on the metabolic, anthropometric and oxidative stress parameters of women with metabolic syndrome.
Thirty sedentary female patients, age range 30-60 years, were invited to participate in a 6-week cardiovascular physical programme. The training consisted of 60-min sessions of aerobic and strength exercises performed 3 times a week; a total of 18 sessions. Anthropometric data, functional exercise capacity, general biochemical profile, serum lipid peroxidation, superoxide dismutase and catalase activity in erythrocytes were evaluated according to standardized protocols. Peripheral vascular function was assessed using applanation tonometry. All assessments were performed before and after the training programme.
The physical programme proved effective in improving the distance covered in the 6-min walk test and in reducing arterial pressure levels, pulse pressure and the Augmentation Index, without modifying heart rate. The plasma thiobarbituric acid reactive substances levels, indicators of oxidative stress, were significantly decreased after the programme. Superoxide dismutase activity was increased in erythrocyte lysates, with no significant change in catalase activity. Waist circumference was significantly decreased compared with baseline. The distance covered in the 6-min walk test was significantly greater after the short-term cardiovascular training.
These findings indicate that short-term combined aerobic and strength training may represent an important non-pharmacological approach for treating individuals with metabolic syndrome.
评估短期心血管体能方案对代谢综合征女性患者代谢、人体测量学和氧化应激参数的影响。
邀请 30 名久坐的女性患者（年龄 30-60 岁）参加为期 6 周的心血管体能方案。训练包括每周 3 次、每次 60 分钟的有氧运动和力量训练；共 18 次。根据标准化方案评估人体测量数据、功能运动能力、一般生化特征、血清脂质过氧化、红细胞中超氧化物歧化酶和过氧化氢酶活性。使用平板测压法评估外周血管功能。所有评估均在训练计划前后进行。
该体能方案可有效提高 6 分钟步行试验的距离，降低动脉压水平、脉压和增强指数，而不改变心率。方案后，血浆硫代巴比妥酸反应物质水平（氧化应激的指标）显著降低。红细胞裂解物中超氧化物歧化酶活性增加，过氧化氢酶活性无明显变化。与基线相比，腰围明显减小。6 分钟步行试验的距离在短期心血管训练后显著增加。
这些发现表明，短期联合有氧运动和力量训练可能是治疗代谢综合征患者的一种重要非药物治疗方法。
