Coutinho R A, Boer K, Schutte M F, van der Velde W J, Mulder-Folkerts D K, van Doornum G J
Gemeentelijke Geneeskundige en Gezondheidsdienst, sector Volksgezondheid en Milieu, Amsterdam.
Ned Tijdschr Geneeskd. 1990 Jun 30;134(26):1264-6.
The HIV prevalence among pregnant women in 3 hospitals in Amsterdam was found to be 0.28% in 1988. As the population of these 3 hospitals is not representative of all pregnant women in Amsterdam, this study--which is done on a voluntary basis--in 1989 was slowly extended to all hospitals, clinics and practices of midwives. Of 5,176 pregnant women who were eligible in 1989, 4,812 (93.0%) participated in the study. Non-Dutch women were overrepresented among the refusers. Antibodies to HIV were found in 5/4, 812 women (0.10%, 95% confidence interval 0.01-0.19) and all 5 infected women reported an AIDS risk factor either for themselves or for their present or previous partner(s). Three of the infected women were only tested during the third trimester; the 2 others were tested in the first trimester of their pregnancy and underwent an abortion. The prevalence in 1989 was lower than that found in 1988 and this may have been influenced by an increased effort to counsel seropositive women--and especially intravenous drug users--on the risk of pregnancy.
1988年,阿姆斯特丹3家医院的孕妇中艾滋病毒感染率为0.28%。由于这3家医院的人群不能代表阿姆斯特丹所有孕妇,1989年这项基于自愿的研究逐渐扩展到所有医院、诊所和助产士执业点。1989年符合条件的5176名孕妇中,4812人(93.0%)参与了研究。拒绝者中非荷兰裔女性占比过高。4812名女性中有5人(0.10%,95%置信区间0.01 - 0.19)检测出艾滋病毒抗体,所有5名感染女性均报告自身或其现任或前任伴侣存在艾滋病风险因素。3名感染女性仅在孕晚期接受检测;另外2人在孕早期接受检测并进行了人工流产。1989年的感染率低于1988年,这可能是由于加大了对血清反应阳性女性——尤其是静脉注射吸毒者——进行妊娠风险咨询的力度。