Bindels P J, Mulder-Folkerts D K, Boer K, Schutte M F, van der Velde W j, Wong F J, van den Hoek A J, van Doornum G J, Coutinho R A
Municipal Health Service, University of Amsterdam.
Eur J Epidemiol. 1994 Jun;10(3):331-8. doi: 10.1007/BF01719358.
The objective of the study was to monitor the HIV prevalence in the years 1988-1991 among pregnant women in the Amsterdam region, visitors to an abortion clinic and 3 outpatient infertility clinics. All women attending these clinics were asked to participate in the study on a voluntary basis and were tested with informed consent. The women were questioned about risk-bearing behaviour of themselves and their sexual partner(s). In the period 1988-1991, of the 23,827 eligible pregnant women, 22,165 women participated (93.0%). Twenty-seven women were found to be positive for HIV antibodies (0.12%, 95% CI: 0.08%-0.17%), of whom twenty belonged to a known HIV risk group or had a partner who belonged to one of these groups and 7 women had no known HIV risk. Seventeen of the 27 women had a foreign nationality. The annual HIV prevalence among pregnant women was: 1988: 0.28%; 1989: 0.10%; 1990: 0.10%; 1991: 0.11%. In the years 1990 and 1991, of the 1,128 eligible women visiting the abortion clinic 953 (84.5%) were tested. Eleven women were HIV-seropositive (1.15%, 95% CI: 0.6%-2.0%), of whom 9 were from an AIDS endemic region, 1 woman had a partner from this region and 1 woman had no known HIV risk. Four African women had HIV-2 antibodies. At the 3 outpatient infertility clinics 1 woman was found to be HIV-positive (0.13%; 95% CI: 0.02-0.9). She had no other risk than a partner from an AIDS endemic area. In the Amsterdam region there was a steady and low HIV prevalence (0.1%) among pregnant women through the years 1988-1991. The prevalence in the abortion clinic was ten times higher. The program was able to detect possible high risk groups within the population. Migration and travelling can play an important role in the spread of HIV in the general heterosexual population.
该研究的目的是监测1988 - 1991年期间阿姆斯特丹地区孕妇、一家堕胎诊所的访客以及三家门诊不孕症诊所患者中的艾滋病毒流行情况。所有到这些诊所就诊的女性均被邀请自愿参与该研究,并在获得知情同意后接受检测。这些女性被询问了自身及其性伴侣的风险行为。在1988 - 1991年期间,23827名符合条件的孕妇中,有22165名女性参与(93.0%)。发现27名女性的艾滋病毒抗体呈阳性(0.12%,95%置信区间:0.08% - 0.17%),其中20名女性属于已知的艾滋病毒风险群体或其伴侣属于这些群体之一,7名女性无已知的艾滋病毒风险。27名女性中有17名具有外国国籍。孕妇中的艾滋病毒年流行率分别为:1988年:0.28%;1989年:0.10%;1990年:0.10%;1991年:0.11%。在1990年和1991年,1128名符合条件的堕胎诊所访客中,953名(84.5%)接受了检测。11名女性艾滋病毒血清呈阳性(1.15%,95%置信区间:0.6% - 2.0%),其中9名来自艾滋病流行地区,1名女性的伴侣来自该地区,1名女性无已知的艾滋病毒风险。4名非洲女性有艾滋病毒-2抗体。在三家门诊不孕症诊所,发现1名女性艾滋病毒呈阳性(0.13%;95%置信区间:0.02 - 0.9)。除了有一名来自艾滋病流行地区的伴侣外,她没有其他风险。在1988 - 1991年期间,阿姆斯特丹地区孕妇中的艾滋病毒流行率稳定且较低(0.1%)。堕胎诊所中的流行率则高出十倍。该项目能够在人群中检测出可能的高风险群体。移民和旅行在艾滋病毒在普通异性恋人群中的传播中可能起重要作用。