Luo Yu, Bao Li, Wang Mu, Guo Hui
Department of Obstetrics Nursing, West China Second University Hospital, West China School of Nursing, Sichuan University, Chengdu, China.
Key Laboratory of Birth Defects and Related Diseases of Women and Children, Ministry of Education, Sichuan University, Chengdu, China.
Front Pediatr. 2022 Aug 15;10:899519. doi: 10.3389/fped.2022.899519. eCollection 2022.
To analyze the prevalence and Years Lived with Disability of Asthma in children under 5 years old and the time trends in Sichuan Southwest China from 1990-2019.
Based on the results of the Global Burden of Disease Study 2019 (GBD2019), we present the time trend, sex specific prevalence, Years Lived with Disability (YLDs) and deaths due to asthma under 5 years old in Sichuan and compared them with national indicators in the same period.
The number of children under 5 years old with asthma decreased overall from 1990 to 2007 and increased overall from 2008 to 2019. The time trend of prevalence rate was similar. In 2019, over 111 thousands children under 5 years old suffered from asthma, the prevalence rate was 2,584 per 100 thousand, YLDs was 4.5 thousands, and YLDs rate was 105 per 100 thousand in Sichuan. Compared with 1990, the number of patients decreased by 48.6%, the prevalence increased by 9.4%, the YLDs decreased by 48.9%, and the YLDs rate increased by 9.7% in 2019. The increase in the prevalence and YLDs rate of asthma children in Sichuan was higher than the national overall, but the number of asthma deaths and deaths rate in Sichuan and the whole nation all decreased.
The results in Sichuan Southwest China show the prevalence and YLDs of asthma children under 5 years old increased over the past 30 years, and were higher than the overall increase in China. Male children are the key population of increasing asthma disease burden and deserves more attention. More targeted prevention and control measures are still needed to reduce the incidence of asthma.
分析1990 - 2019年中国西南部四川省5岁以下儿童哮喘的患病率和残疾生存年数及其时间趋势。
基于2019年全球疾病负担研究（GBD2019）的结果，我们呈现了四川省5岁以下儿童哮喘的时间趋势、性别特异性患病率、残疾生存年数（YLDs）和哮喘死亡情况，并与同期全国指标进行比较。
1990年至2007年，5岁以下哮喘儿童数量总体呈下降趋势，2008年至2019年总体呈上升趋势。患病率的时间趋势相似。2019年，四川省超过11.1万名5岁以下儿童患有哮喘，患病率为每10万人2584例，YLDs为4500例，YLDs率为每10万人105例。与1990年相比，2019年患者数量减少了48.6%，患病率上升了9.4%，YLDs减少了48.9%，YLDs率上升了9.7%。四川省哮喘儿童患病率和YLDs率的上升高于全国总体水平，但四川省和全国的哮喘死亡人数及死亡率均有所下降。
中国西南部四川省的结果显示，过去30年5岁以下哮喘儿童的患病率和YLDs有所增加，且高于全国总体增长水平。男童是哮喘疾病负担增加的关键人群，值得更多关注。仍需要采取更有针对性的预防和控制措施来降低哮喘的发病率。
