术后乳房手术后血清肿形成的潜在风险因素——一项前瞻性研究。
Potential Risk Factors Influencing the Formation of Postoperative Seroma After Breast Surgery - A Prospective Study.
机构信息
Department of Obstetrics and Gynecology, University Medicine Greifswald, Greifswald, Germany;
Department of Oral and Maxillofacial Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
出版信息
Anticancer Res. 2021 Feb;41(2):859-867. doi: 10.21873/anticanres.14838.
BACKGROUND/AIM: This trial intended to identify patient- and therapy-specific risk factors influencing the genesis of seroma and the extent of its formation.
PATIENTS AND METHODS
Within a prospective randomized controlled trial, 70 patients (n=35 TissuGlu; n=35 drain) underwent a mastectomy with or without sentinel lymphonodectomy. Specific seroma-associated risk factors were recorded. Regular outpatient aftercare was performed during a 90-day postoperative follow-up.
RESULTS
A statistically significant increase in the postoperative seroma rate was demonstrated for those with pre-adiposity compared to normal body weight (p=0.016), as well as for the state of health evaluated by the score of American Society of Anesthesiologists (ASA) (ASA III compared to I; p=0.046), the presence of diabetes mellitus (p<0.001) and the reduction of the length of the surgical procedure (p=0.044).
CONCLUSION
A high body mass index, a poor state of health (ASA score), and diabetes mellitus, as well as a shorter duration of surgery, favor the incidence of postoperative seroma.
背景/目的：本试验旨在确定影响血清肿发生和形成程度的患者和治疗相关的风险因素。
患者和方法
在一项前瞻性随机对照试验中，70 名患者（n=35 例 TissuGlu；n=35 例引流）接受了乳房切除术和（或）前哨淋巴结切除术。记录特定的与血清肿相关的风险因素。在术后 90 天的随访期间，进行常规的门诊随访。
结果
与正常体重相比，超重患者的术后血清肿发生率显著增加（p=0.016），美国麻醉医师协会（ASA）评分评估的健康状况（ASA III 级与 I 级相比；p=0.046）、糖尿病（p<0.001）以及手术时间缩短（p=0.044）也是如此。
结论
高身体质量指数、较差的健康状况（ASA 评分）和糖尿病，以及手术时间缩短，都有利于术后血清肿的发生。
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