放松干预对HIV血清阳性女性皮质醇水平的影响。
The effect of relaxation interventions on cortisol levels in HIV-seropositive women.
作者信息
Jones Deborah, Owens Mary, Kumar Mahendra, Cook Ryan, Weiss Stephen M
出版信息
J Int Assoc Provid AIDS Care. 2014 Jul-Aug;13(4):318-23. doi: 10.1177/2325957413488186.
Abstract
PURPOSE
Activation of the hypothalamic-pituitary-adrenal axis, assessed in terms of cortisol levels, may enhance the ability of HIV to infect lymphocytes and downregulate the immune system, accelerating disease progression. This study sought to determine the effects of relaxation techniques on cortisol levels in HIV-seropositive women.
METHODS
Women (n = 150) were randomized to a group cognitive-behavioral stress management (CBSM) condition or an individual information condition and underwent 3 types of relaxation training (progressive muscle relaxation, imagery, and autogenic training). Cortisol levels were obtained pre- and postrelaxation.
RESULTS
Guided imagery was effective in reducing cortisol in the group condition (t = 3.90, P < .001), and muscle relaxation reduced cortisol in the individual condition (t = 3.1 I, P = .012). Among participants in the group condition attending all sessions, the magnitude of pre- to postsession reduction became greater over time.
CONCLUSIONS
Results suggest that specific relaxation techniques may be partially responsible for cortisol decreases associated with relaxation and CBSM.
摘要
目的
通过皮质醇水平评估下丘脑-垂体-肾上腺轴的激活情况，其可能会增强人类免疫缺陷病毒（HIV）感染淋巴细胞的能力并下调免疫系统，从而加速疾病进展。本研究旨在确定放松技巧对HIV血清阳性女性皮质醇水平的影响。
方法
150名女性被随机分为团体认知行为压力管理（CBSM）组或个体信息组，并接受3种放松训练（渐进性肌肉松弛、意象训练和自生训练）。在放松训练前后测量皮质醇水平。
结果
在团体训练中，引导意象训练能有效降低皮质醇水平（t = 3.90，P < .001），而在个体训练中，肌肉松弛训练能降低皮质醇水平（t = 3.11，P = .012）。在团体训练中参加了所有课程的参与者中，随着时间的推移，训练前后皮质醇水平降低的幅度越来越大。
结论
结果表明，特定的放松技巧可能部分导致了与放松和CBSM相关的皮质醇水平下降。
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