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美国成年人中阻塞性和限制性肺功能的流行趋势:1988-1994 年至 2007-2010 年全国健康和营养检查调查的结果。

Trends in the prevalence of obstructive and restrictive lung function among adults in the United States: findings from the National Health and Nutrition Examination surveys from 1988-1994 to 2007-2010.

机构信息

Division of Population Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA.

Department of Preventive Medicine and Environmental Health, University of Kentucky College of Public Health, Lexington, KY.

出版信息

Chest. 2013 May;143(5):1395-1406. doi: 10.1378/chest.12-1135.

Abstract

BACKGROUND

National spirometric surveillance data in the United States were last collected during 1988-1994. The objective of this study was to provide current estimates for obstructive and restrictive impairment of lung function and to examine changes since 1988-1994.

METHODS

We used data from 14,360 participants aged 20 to 79 years from the National Health and Nutrition Examination Survey (NHANES) III (1988-1994) and 9,024 participants from NHANES 2007-2010. Spirometry was conducted using the same spirometers and generally similar protocols.

RESULTS

During 2007-2010, 13.5% (SE, 0.6) of participants had evidence of airway obstruction (FEV1/FVC < 0.70): 79.9% of adults had normal lung function, 6.5% had a restrictive impairment, 7.5% had mild obstruction, 5.4% had moderate obstruction, and 0.7% had severe obstruction. Although the overall age-adjusted prevalence of any obstruction did not change significantly from 1988-1994 (14.6%) to 2007-2010 (13.5%) (P = .178), significant decreases were noted for participants aged 60 to 79 years and for Mexican Americans. The prevalence of current smoking remained high among participants with moderate (48.4%) and severe (37.9%) obstructive impairments. A significant decline in current smoking occurred only among those with normal lung function (P < .05).

CONCLUSION

Spirometry revealed little change in the prevalence of any obstructive and restrictive impairment in lung function during 2007-2010, compared with 1988-1994.

摘要

背景

美国的国家肺量计监测数据最近一次是在 1988-1994 年收集的。本研究的目的是提供当前阻塞性和限制性肺功能障碍的估计值,并检查自 1988-1994 年以来的变化。

方法

我们使用了来自国家健康和营养检查调查(NHANES)III(1988-1994 年)的 14360 名 20 至 79 岁的参与者和 NHANES 2007-2010 年的 9024 名参与者的数据。肺量计检查使用相同的肺量计,通常使用相似的方案。

结果

在 2007-2010 年期间,有 13.5%(SE,0.6)的参与者有气道阻塞的证据(FEV1/FVC < 0.70):79.9%的成年人有正常的肺功能,6.5%有限制性障碍,7.5%有轻度阻塞,5.4%有中度阻塞,0.7%有重度阻塞。尽管从 1988-1994 年(14.6%)到 2007-2010 年(13.5%),任何阻塞的总体年龄调整患病率没有显著变化(P =.178),但在 60 至 79 岁的参与者和墨西哥裔美国人中,这种情况有显著下降。在有中度(48.4%)和重度(37.9%)阻塞性障碍的参与者中,当前吸烟的患病率仍然很高。只有在正常肺功能的参与者中,当前吸烟的情况才显著下降(P <.05)。

结论

与 1988-1994 年相比,2007-2010 年期间,肺量计检查显示任何阻塞性和限制性肺功能障碍的患病率几乎没有变化。

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