• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

830纳米发光二极管疗法对急性眼带状疱疹的影响：一项初步研究。

The Effects of 830 nm Light-Emitting Diode Therapy on Acute Herpes Zoster Ophthalmicus: A Pilot Study.

作者信息

Park Kui Young, Han Tae Young, Kim In Su, Yeo In Kwon, Kim Beom Joon, Kim Myeung Nam

机构信息

Department of Dermatology, Chung-Ang University College of Medicine, Seoul, Korea.

出版信息

Ann Dermatol. 2013 May;25(2):163-7. doi: 10.5021/ad.2013.25.2.163. Epub 2013 May 10.

DOI:10.5021/ad.2013.25.2.163
PMID:23717006
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3662908/
Abstract

BACKGROUND

Skin lesions and pain are the most distinctive features of herpes zoster. Light-emitting diode (LED) therapy is an effective treatment known for its wound-healing effects.

OBJECTIVE

To determine whether the LED treatment affects wound healing and acute pain in acute herpes zoster ophthalmicus.

METHODS

We recruited 28 consecutive Korean patients with acute herpes zoster ophthalmicus for the study. In the control group (group A), 14 subjects received oral famcyclovir. In the experimental group (group B), 14 subjects received oral famcyclovir and 830 nm LED phototherapy on days 0, 4, 7, and 10. In order to estimate the time for wound healing, we measured the duration from the vesicle formation to when the lesion crust fell off. The visual analogue scale (VAS) was used for the estimation of pain on days 4, 7, 10, and 14.

RESULTS

The mean time required for wound healing was 13.14±2.34 days in group B and 15.92±2.55 days in group A (p=0.006). From day 4, the mean VAS score showed a greater improvement in group B, compared with group A. A marginal but not statistically significant difference in the VAS scores was observed between the two groups (p=0.095).

CONCLUSION

LED treatment for acute herpes zoster ophthalmicus leads to faster wound healing and a lower pain score.

摘要

背景

皮肤病变和疼痛是带状疱疹最显著的特征。发光二极管（LED）疗法是一种以其伤口愈合效果而闻名的有效治疗方法。

目的

确定LED治疗是否会影响急性眼部带状疱疹的伤口愈合和急性疼痛。

方法

我们连续招募了28名患有急性眼部带状疱疹的韩国患者进行研究。在对照组（A组）中，14名受试者接受口服泛昔洛韦治疗。在实验组（B组）中，14名受试者在第0、4、7和10天接受口服泛昔洛韦和830 nm LED光疗。为了估计伤口愈合时间，我们测量了从水疱形成到病变结痂脱落的持续时间。在第4、7、10和14天使用视觉模拟量表（VAS）评估疼痛程度。

结果

B组伤口愈合的平均时间为13.14±2.34天，A组为15.92±2.55天（p=0.006）。从第4天起，B组的平均VAS评分比A组有更大改善。两组之间的VAS评分存在微小但无统计学意义的差异（p=0.095）。

结论

LED治疗急性眼部带状疱疹可使伤口愈合更快，疼痛评分更低。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1965/3662908/24cf7fee481e/ad-25-163-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1965/3662908/b21400c571f4/ad-25-163-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1965/3662908/a12e94202309/ad-25-163-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1965/3662908/bee1b190441c/ad-25-163-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1965/3662908/24cf7fee481e/ad-25-163-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1965/3662908/b21400c571f4/ad-25-163-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1965/3662908/a12e94202309/ad-25-163-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1965/3662908/bee1b190441c/ad-25-163-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1965/3662908/24cf7fee481e/ad-25-163-g004.jpg

相似文献

1
The Effects of 830 nm Light-Emitting Diode Therapy on Acute Herpes Zoster Ophthalmicus: A Pilot Study.830纳米发光二极管疗法对急性眼带状疱疹的影响：一项初步研究。
Ann Dermatol. 2013 May;25(2):163-7. doi: 10.5021/ad.2013.25.2.163. Epub 2013 May 10.
2
Valacyclovir versus acyclovir for the treatment of herpes zoster ophthalmicus in immunocompetent patients.伐昔洛韦与阿昔洛韦治疗免疫功能正常患者的眼部带状疱疹
Cochrane Database Syst Rev. 2016 Nov 14;11(11):CD011503. doi: 10.1002/14651858.CD011503.pub2.
3
Comparison of the efficacy and safety of valaciclovir and acyclovir for the treatment of herpes zoster ophthalmicus.伐昔洛韦与阿昔洛韦治疗眼部带状疱疹的疗效及安全性比较。
Ophthalmology. 2000 Aug;107(8):1507-11. doi: 10.1016/s0161-6420(00)00222-0.
4
Oral acyclovir for herpes zoster ophthalmicus.口服阿昔洛韦治疗眼部带状疱疹。
Ophthalmology. 1992 Jul;99(7):1062-70; discussion 1070-1. doi: 10.1016/s0161-6420(92)31849-4.
5
Herpes zoster ophthalmicus in olmsted county, Minnesota: have systemic antivirals made a difference?明尼苏达州奥姆斯特德县的眼部带状疱疹：全身性抗病毒药物有作用吗？
Arch Ophthalmol. 2003 Mar;121(3):386-90. doi: 10.1001/archopht.121.3.386.
6
Association of herpes zoster ophthalmicus with acquired immunodeficiency syndrome and acute retinal necrosis.眼部带状疱疹与获得性免疫缺陷综合征及急性视网膜坏死的关联。
Am J Ophthalmol. 1993 Sep 15;116(3):297-301. doi: 10.1016/s0002-9394(14)71346-7.
7
Orbital apex syndrome: an unusual complication of herpes zoster ophthalmicus.眶尖综合征：眼部带状疱疹的一种罕见并发症。
BMC Infect Dis. 2015 Jan 31;15:33. doi: 10.1186/s12879-015-0760-z.
8
Acute Orbital Syndrome in Herpes Zoster Ophthalmicus: Clinical Features of 7 Cases.眼部带状疱疹所致急性眼眶综合征：7例临床特征
Ophthalmic Plast Reconstr Surg. 2017 May/Jun;33(3):173-177. doi: 10.1097/IOP.0000000000000688.
9
Oral acyclovir in herpes zoster ophthalmicus.口服阿昔洛韦治疗眼部带状疱疹。
Curr Eye Res. 1991;10 Suppl:177-82. doi: 10.3109/02713689109020376.
10
Longitudinal analysis of varicella-zoster virus DNA on the ocular surface associated with herpes zoster ophthalmicus.与眼部带状疱疹相关的眼表水痘-带状疱疹病毒DNA的纵向分析。
Am J Ophthalmol. 2001 Jan;131(1):25-9. doi: 10.1016/s0002-9394(00)00652-8.

引用本文的文献

1
Clinical efficacy of LED golden light combined with acyclovir in the treatment of herpes zoster: a single-center prospective study.LED 金光照联合阿昔洛韦治疗带状疱疹的临床疗效：一项单中心前瞻性研究。
Lasers Med Sci. 2023 Jul 5;38(1):157. doi: 10.1007/s10103-023-03817-y.
2
Red LED light therapy associated with epidermal growth factor on wound repair process in rats.红光 LED 光疗联合表皮生长因子对大鼠创面修复过程的影响。
Lasers Med Sci. 2023 Jan 10;38(1):36. doi: 10.1007/s10103-022-03701-1.
3
Effect of low-level light therapy in patients with dry eye: a prospective, randomized, observer-masked trial.

本文引用的文献

1
Phototherapy promotes healing of chronic diabetic leg ulcers that failed to respond to other therapies.光疗可促进对其他治疗无反应的慢性糖尿病腿部溃疡的愈合。
Lasers Surg Med. 2009 Aug;41(6):433-41. doi: 10.1002/lsm.20789.
2
Phototherapy improves healing of chronic venous ulcers.光疗可改善慢性静脉溃疡的愈合。
Photomed Laser Surg. 2009 Feb;27(1):111-8. doi: 10.1089/pho.2008.2398.
3
Light-emitting diodes (LEDs) in dermatology.皮肤科中的发光二极管（LED）
低水平光疗法治疗干眼症患者的效果：一项前瞻性、随机、观察者设盲试验。
Sci Rep. 2022 Mar 4;12(1):3575. doi: 10.1038/s41598-022-07427-6.
4
Successful Treatment of Digital Ischemia Following a Carbon Dioxide Laser and Tourniquet for a Digital Procedure With Adjuvant Low-Level Laser Therapy.二氧化碳激光和止血带用于手指手术并辅助低强度激光治疗后手指缺血的成功治疗
J Lasers Med Sci. 2019 Summer;10(3):254-256. doi: 10.15171/jlms.2019.41. Epub 2019 Jul 6.
5
Local and systemic effects of low-level light therapy with light-emitting diodes to improve erythema after fractional ablative skin resurfacing: a controlled study.采用发光二极管进行低强度光疗改善剥脱性皮肤磨削术后红斑的局部和全身效应：一项对照研究。
Lasers Med Sci. 2019 Mar;34(2):343-351. doi: 10.1007/s10103-018-2599-1. Epub 2018 Aug 3.
6
Light-emitting diodes in dermatology: A systematic review of randomized controlled trials.皮肤科中的发光二极管：随机对照试验的系统评价
Lasers Surg Med. 2018 Jan 22;50(6):613-28. doi: 10.1002/lsm.22791.
7
The Histopathological Investigation of Red and Blue Light Emitting Diode on Treating Skin Wounds in Japanese Big-Ear White Rabbit.红光和蓝光发光二极管治疗日本大耳白兔皮肤伤口的组织病理学研究
PLoS One. 2016 Jun 27;11(6):e0157898. doi: 10.1371/journal.pone.0157898. eCollection 2016.
8
Controlling periodontal bone levels with multiple LED irradiations.通过多次LED照射控制牙周骨水平。
Lasers Med Sci. 2015 Feb;30(2):741-6. doi: 10.1007/s10103-013-1416-0. Epub 2013 Aug 11.
Semin Cutan Med Surg. 2008 Dec;27(4):227-38. doi: 10.1016/j.sder.2008.08.003.
4
Low-level laser therapy in acute pain: a systematic review of possible mechanisms of action and clinical effects in randomized placebo-controlled trials.低强度激光疗法治疗急性疼痛：对随机安慰剂对照试验中可能的作用机制和临床效果的系统评价
Photomed Laser Surg. 2006 Apr;24(2):158-68. doi: 10.1089/pho.2006.24.158.
5
A study to determine the efficacy of combination LED light therapy (633 nm and 830 nm) in facial skin rejuvenation.一项旨在确定联合使用LED光疗法（633纳米和830纳米）对面部皮肤年轻化效果的研究。
J Cosmet Laser Ther. 2005 Dec;7(3-4):196-200. doi: 10.1080/14764170500370059.
6
The efficacy of low-power lasers in tissue repair and pain control: a meta-analysis study.低功率激光在组织修复和疼痛控制中的疗效：一项荟萃分析研究。
Photomed Laser Surg. 2004 Aug;22(4):323-9. doi: 10.1089/pho.2004.22.323.
7
Increased fibroblast proliferation induced by light emitting diode and low power laser irradiation.发光二极管和低功率激光照射诱导成纤维细胞增殖增加。
Lasers Med Sci. 2003;18(2):95-9. doi: 10.1007/s10103-003-0262-x.
8
Does nitric oxide modulate mitochondrial energy generation and apoptosis?一氧化氮是否调节线粒体能量生成和细胞凋亡？
Nat Rev Mol Cell Biol. 2002 Mar;3(3):214-20. doi: 10.1038/nrm762.
9
Effect of NASA light-emitting diode irradiation on wound healing.美国国家航空航天局发光二极管照射对伤口愈合的影响。
J Clin Laser Med Surg. 2001 Dec;19(6):305-14. doi: 10.1089/104454701753342758.