Østmarka Psychiatric Department, St. Olav's University Hospital, Trondheim 7441, Norway.
BMC Psychiatry. 2013 May 30;13:156. doi: 10.1186/1471-244X-13-156.
Obsessive-compulsive disorder (OCD) in patients with psychotic disorders has been reported to be a frequent co-morbid disorder in patients with psychotic disorders. The aim of the study determine the prevalence of OCD in first-episode psychosis and the relationship with clinical characteristics.
First-episode psychosis patients (N = 246) consecutively admitted to a comprehensive early psychosis program were assessed for OCD with the Structured Clinical Interview for DSM-IV. Symptom assessment measures were the Positive and Negative Syndrome Scale, Global Assessment of Functioning, and the Clinician Rating Scale.
Twenty-six patients (10.6%) fulfilled the criteria for OCD. Patients with comorbid OCD were younger, had more depressive symptoms and a higher rate of suicidal plans or attempts at index point compared to patients without OCD. The two groups did not differ with respect to other demographic variables or severity of psychotic symptoms.
OCD is a significant comorbid disorder in patients with first-episode psychosis. Since treatment procedures are different, systematic screening for OCD is warranted.
精神障碍患者的强迫症（OCD）已被报道为精神障碍患者中常见的共病障碍。本研究旨在确定首发精神病患者中 OCD 的患病率及其与临床特征的关系。
连续收治于综合早期精神病项目的首发精神病患者（N=246）采用DSM-IV 定式临床访谈进行 OCD 评估。症状评估量表包括阳性和阴性症状量表、总体功能评估和临床医生评定量表。
26 名患者（10.6%）符合 OCD 标准。与无 OCD 的患者相比，合并 OCD 的患者更年轻，抑郁症状更多，且在指数点时自杀计划或企图的发生率更高。两组在其他人口统计学变量或精神病症状严重程度方面无差异。
OCD 是首发精神病患者的一种重要共病障碍。由于治疗程序不同，系统筛查 OCD 是必要的。
