Department of Food and Nutrition, Korea University, Seoul, Korea.
J Cosmet Dermatol. 2013 Jun;12(2):137-43. doi: 10.1111/jocd.12038.
This study was performed to investigate the anti-wrinkle effects of topical applications of green tea extract with high antioxidant activity by tannase treatment. Increases in gallic acid (GA), (-)-epigallocatechin (EGC), and (-)-epicatechin (EC) were observed in the green tea extract after tannase treatment.
This study was performed to investigate the anti-wrinkle effects of topical applications of green tea extract exhibiting high antioxidant activity after tannase treatment.
Subjects, randomly divided into two groups, received the application of either tannase-converted green tea extract (TGE) or normal green tea extract (NGE) on their crow's feet for 8 weeks. The anti-wrinkle effects were evaluated with two methods: (i) self-assessment; and (ii) average roughness of skin surface (R(a), R(z), and R(t) value) using skin replica and Skin-Visiometer SV 600.
The scavenging abilities of TGE against radicals were significantly higher compared to NGE. The evaluation of skin wrinkle index values after 8 weeks of treatment showed that reductions of R(a), R(z), and R(t) values in the TGE group were significantly greater than in the NGE group, which indicated that tannase treatment improved the anti-wrinkle effects of green tea extract. According to the overall ratings for wrinkle treatment by applying the formulations, most of the TGE group (63.60%) reported marked or moderate improvement in wrinkles compared with only 36.30% of the NGE group.
Tannase treatment can improve the antioxidant activity of green tea extract, conferring anti-wrinkle activities. These results suggest that TGE may have beneficial properties as an anti-wrinkle agent.
本研究旨在探讨经单宁酶处理后具有高抗氧化活性的绿茶提取物的局部应用的抗皱效果。在单宁酶处理后，绿茶提取物中的没食子酸（GA）、（-）-表没食子儿茶素（EGC）和（-）-表儿茶素（EC）含量增加。
本研究旨在探讨经单宁酶处理后具有高抗氧化活性的绿茶提取物的局部应用的抗皱效果。
将受试者随机分为两组，分别在鱼尾纹处涂抹单宁酶转化的绿茶提取物（TGE）或普通绿茶提取物（NGE），持续 8 周。采用两种方法评估抗皱效果：（i）自我评估；（ii）使用皮肤复制品和 Skin-Visiometer SV 600 评估皮肤表面粗糙度（R(a)、R(z)和 R(t)值）。
TGE 对自由基的清除能力明显高于 NGE。经过 8 周的治疗后，皮肤皱纹指数值的评估表明，TGE 组的 R(a)、R(z)和 R(t)值降低幅度明显大于 NGE 组，这表明单宁酶处理改善了绿茶提取物的抗皱效果。根据应用配方对面部皱纹治疗的整体评价，TGE 组中（63.60%）大多数报告皱纹有明显或中度改善，而 NGE 组中只有（36.30%）报告有明显或中度改善。
单宁酶处理可以提高绿茶提取物的抗氧化活性，赋予其抗皱活性。这些结果表明，TGE 可能具有作为抗皱剂的有益特性。
