Tennent Institute of Ophthalmology, Gartnavel General Hospital, UK.
Scott Med J. 2013 May;58(2):e1-6. doi: 10.1177/0036933013482647.
Endogenous endophthalmitis is a sight-threatening condition caused by microorganisms crossing the blood-ocular barrier and inducing profound intraocular inflammation.
A 65-year-old female experienced bilateral loss of vision after developing infective endocarditis as a complication of combined Bentall procedure and coronary artery bypass grafting. She was diagnosed with bilateral endogenous endophthalmitis secondary to Serratia marcescens. Despite aggressive treatment with intravitreal injections of antibiotics and steroids, intensive topical and systemic antibiotic therapy, there was permanent loss of sight in both eyes.
The case highlights the importance of early recognition of the symptoms and signs of endogenous endophthalmitis in any patient with systemic infection by all clinicians and the necessity of prompt ophthalmological referral if a useful level of vision is to be preserved.
内源性眼内炎是一种由微生物穿过血眼屏障并引起严重眼内炎症而导致的威胁视力的疾病。
一名 65 岁女性在因合并的 Bentall 手术和冠状动脉旁路移植术后发生感染性心内膜炎并发症后，出现双侧视力丧失。她被诊断为双侧内源性眼内炎，继发于粘质沙雷氏菌感染。尽管通过玻璃体腔内注射抗生素和类固醇、强化局部和全身抗生素治疗进行了积极治疗，但双眼视力仍永久丧失。
该病例强调了所有临床医生都要重视任何全身感染患者出现内源性眼内炎的症状和体征，并强调如果要保留有用的视力，则需要及时转至眼科就诊。
