Kurt Raziye Keskin, Aras Zinnur, Silfeler Dilek Benk, Kunt Cigdem, Islimye Mine, Kosar Ozlem
Department of Obstetrics and Gynecology, Antakya State Hospital of Obstetrics and Child Care, Hatay, Turkey
Department of Obstetrics and Gynecology, Antakya State Hospital of Obstetrics and Child Care, Hatay, Turkey.
Clin Appl Thromb Hemost. 2015 Mar;21(2):128-31. doi: 10.1177/1076029613490827. Epub 2013 May 31.
Although the relationship between red cell distribution width (RDW) and hypertension has been well documented, there is an absence of data on the association between RDW and preeclampsia. In the present study, we have aimed to investigate the correlation of RDW with preeclampsia and its severity.
The study population consisted of 52 (35 mild and 17 severe) patients with preeclampsia and 50 control pregnancy patients. For the entire study population, baseline RDW was measured using an automatic blood counter.
Although there were no significant differences between the preeclampsia group and the control group in terms of hemoglobin and platelet counts, the RDW (14.1 ± 1.1 vs 16.9 ± 1.7, P < .001), systolic and diastolic blood pressure, proteinuria, white blood cell, and high-sensitivity C-reactive protein levels were significantly higher in the preeclampsia group. Moreover, subgroup analysis revealed that RDW levels were significantly increased in patients with severe preeclampsia when compared to the patients with mild preeclampsia (18 ± 1.5 vs 16.4 ± 1.5, P < .001).
Our study results revealed that RDW levels were associated with both the presence and the severity of preeclampsia.
尽管红细胞分布宽度（RDW）与高血压之间的关系已有充分记录，但关于RDW与子痫前期之间关联的数据却很缺乏。在本研究中，我们旨在探讨RDW与子痫前期及其严重程度的相关性。
研究人群包括52例（35例轻度和17例重度）子痫前期患者和50例对照妊娠患者。对于整个研究人群，使用自动血液计数器测量基线RDW。
尽管子痫前期组与对照组在血红蛋白和血小板计数方面无显著差异，但子痫前期组的RDW（14.1±1.1对16.9±1.7，P<.001）、收缩压和舒张压、蛋白尿、白细胞以及高敏C反应蛋白水平显著更高。此外，亚组分析显示，与轻度子痫前期患者相比，重度子痫前期患者的RDW水平显著升高（18±1.5对16.4±1.5，P<.001）。
我们的研究结果显示，RDW水平与子痫前期的存在及其严重程度均相关。
