Cha Dong Min, Lee Taeseung, Choe Gheeyoung, Yang Hee Kyung, Hwang Jeong-Min
Department of Ophthalmology, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea.
Korean J Ophthalmol. 2013 Jun;27(3):224-7. doi: 10.3341/kjo.2013.27.3.224. Epub 2013 Apr 25.
Giant cell arteritis (GCA) is a rare disease among Asians. Arteritic anterior ischemic optic neuropathy, which accompanies GCA, has not yet been reported in Koreans. Diagnosis of GCA is difficult if typical symptoms other than visual loss are absent. Here, we report a case of an 83-year-old Korean woman presenting with sudden visual loss in both eyes (oculus uterque, OU). Her visual acuities included perception of light in the right eye (oculus dexter, OD) and perception of hand motion in the left eye (oculus sinister, OS). The results of the Hardy-Rand-Rittler test and Ishihara test showed total dyschromatopsia OU. The Goldmann perimetry test revealed a total field defect OD and paracentral island OS. Fundus examination revealed chalky-white disc swelling OU. Other systemic symptoms and signs were unremarkable. The erythrocyte sedimentation rate, C-reactive protein and platelet count were highly elevated. Temporal artery biopsy revealed multiple lymphocytes and multinucleated giant cells in the arterial media layer. To our knowledge, this is the first report of GCA in a Korean that has been confirmed with temporal artery biopsy. In conclusion, silent GCA can occur in Koreans, and hence, elderly patients presenting with chalky-white disc swelling, and corresponding laboratory findings must be evaluated for GCA.
巨细胞动脉炎(GCA)在亚洲人中是一种罕见疾病。伴有GCA的动脉性前部缺血性视神经病变在韩国人中尚未见报道。如果没有视力丧失以外的典型症状,GCA的诊断就很困难。在此,我们报告一例83岁韩国女性双眼突发视力丧失的病例。她的视力情况为右眼(OD)仅存光感,左眼(OS)仅存手动感。Hardy-Rand-Rittler测试和石原氏色盲测试结果显示双眼完全色盲。Goldmann视野计测试显示右眼全视野缺损,左眼旁中心岛状视野缺损。眼底检查显示双眼视盘呈灰白色肿胀。其他全身症状和体征不明显。红细胞沉降率、C反应蛋白和血小板计数显著升高。颞动脉活检显示动脉中层有多个淋巴细胞和多核巨细胞。据我们所知,这是韩国首例经颞动脉活检确诊的GCA病例。总之,韩国人也可能发生无症状GCA,因此,对于出现视盘灰白色肿胀的老年患者,必须评估其是否患有GCA及相应的实验室检查结果。