Cheng Cheng-Kuo, Lee Chin-Cheng, Huang Kai-Han, Wu Tzu-En, Peng Pai-Huei
Department of Ophthalmology, Shin Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan.
J Formos Med Assoc. 2010 Jul;109(7):550-4. doi: 10.1016/S0929-6646(10)60090-3.
Giant cell arteritis with arteritic anterior ischemic optic neuropathy has rarely been diagnosed in Taiwan. Recently, we encountered a 76-year-old Taiwanese patient who presented with right visual impairment and marked pale swelling of his right disc. He also suffered body weight loss, general malaise and many typical manifestations of giant cell arteritis, such as jaw claudication, a tender, non-pulsating engorgement of his temporal arteries, and a highly elevated erythrocyte sedimentation rate and C-reactive protein level. Biopsy of his right superficial temporal artery revealed a granulomatous inflammation with multinucleated giant cell infiltration. This was a biopsy-proven case of giant cell arteritis with arteritic anterior ischemic optic neuropathy and indicated that although rare, this disease could occur in patients in Taiwan.
巨细胞动脉炎合并动脉炎性前部缺血性视神经病变在台湾鲜有诊断。最近，我们遇到一名76岁的台湾患者，他出现右视力障碍，右视盘明显苍白肿胀。他还伴有体重减轻、全身不适以及巨细胞动脉炎的许多典型表现，如下颌跛行、颞动脉压痛、非搏动性充血，以及红细胞沉降率和C反应蛋白水平显著升高。对其右侧颞浅动脉进行活检，显示为肉芽肿性炎症伴多核巨细胞浸润。这是一例经活检证实的巨细胞动脉炎合并动脉炎性前部缺血性视神经病变病例，表明尽管这种疾病罕见，但在台湾患者中也可能发生。
