School of Pharmacy and Health Professions, Creighton University Medical Center, Omaha, NE, 68168, USA.
Phytother Res. 2014 Apr;28(4):475-9. doi: 10.1002/ptr.5018. Epub 2013 Jun 3.
Shilajit (mumie; moomiyo, mummiyo) has been used for a wide variety of illnesses and conditions for many years. However, relatively few well-controlled human studies have been conducted on the effects of shiliajit, although a growing number of studies have been published in recent years involving animal and in vitro systems. The safety of shilajit is well documented based on animal and human studies. Various research studies indicate that shilajit exhibits antioxidant, anti-inflammatory, adaptogenic, immunomodulatory, and anti-dyslipidemic properties. Animal and human studies indicate that shilajit enhances spermatogenesis. Furthermore, animal and human data support its use as a 'revitalizer', enhancing physical performance and relieving fatigue with enhanced production of ATP. Key constituents in shilajit responsible for these effects appear to be dibenzo-α-pyrones and fulvic acid and their derivatives. Various mechanistic studies provide support for the above observed effects. Additional well-controlled human and animal studies involving the use of standardized products are needed.
喜来芝（天然滋补品；印度草；木乃伊，木乃伊油）已被广泛用于治疗各种疾病和病症多年。然而，尽管近年来涉及动物和体外系统的研究越来越多，但对喜来芝的影响进行的精心控制的人体研究相对较少。基于动物和人体研究，喜来芝的安全性有充分的记录。各种研究表明，喜来芝具有抗氧化、抗炎、适应原性、免疫调节和抗血脂异常的特性。动物和人体研究表明，喜来芝可增强精子发生。此外，动物和人体数据支持将其用作“恢复剂”，通过增强 ATP 的产生来提高身体性能并缓解疲劳。喜来芝中负责这些效果的关键成分似乎是二苯并-α-吡喃酮和富里酸及其衍生物。各种机制研究为上述观察到的效果提供了支持。需要进行更多精心控制的人体和动物研究，涉及使用标准化产品。
