Khatoon Maria, Chaudhari A R, Singh Ramji
Department of Physiology, Mahatma Gandhi Institute of Medical Sciences, Sevagram, Wardha--440 102, India.
Indian J Physiol Pharmacol. 2012 Jul-Sep;56(3):262-6.
The presence of antisperm antibodies in serum may impair sperm function leading to immunological infertility. The aim of study was to determine the presence of antisperm antibodies in the circulating blood of infertile couples. This cross sectional study included 109 couples suffering from infertility for more than one-year duration. Serum antisperm antibodies were determined by Varelisa Sperm Antibodies Enzyme Immunoassay kit. The percentage incidence of antisperm antibodies in infertile men was 30.27% was statistically not significant from the 33.03% incidence in infertile women (P Value > 0.05). In the nineteen (15.59%) couples both the husband as well as wife was positive for sperm antibodies. The presence of antisperm antibodies may impair fertilizing ability therefore its assessment should be consideredas an essential part of infertility management.
血清中抗精子抗体的存在可能会损害精子功能,导致免疫性不孕。本研究的目的是确定不孕夫妇循环血液中抗精子抗体的存在情况。这项横断面研究纳入了109对不孕时间超过一年的夫妇。血清抗精子抗体通过Varelisa精子抗体酶免疫分析试剂盒进行测定。不孕男性中抗精子抗体的发生率为30.27%,与不孕女性33.03%的发生率相比,差异无统计学意义(P值>0.05)。在19对(15.59%)夫妇中,丈夫和妻子的精子抗体均呈阳性。抗精子抗体的存在可能会损害受精能力,因此对其进行评估应被视为不孕治疗的重要组成部分。