Naymagon Steven, Marion James F
Henry D. Janowitz Division of Gastroenterology, Icahn School of Medicine at Mount Sinai, One Gustave Levy Place, New York, NY 10029, USA.
Gastrointest Endosc Clin N Am. 2013 Jul;23(3):679-94. doi: 10.1016/j.giec.2013.03.008. Epub 2013 May 3.
Patients with long-standing inflammatory bowel disease (IBD) have an increased risk of developing colorectal cancer. Performing periodic dysplasia screening and surveillance may diminish this risk. To date, chromoendoscopy is the only technique that has consistently yielded positive results in large, well-designed dysplasia-detection trials. Most major society guidelines endorse chromoendoscopy as an adjunct, accepted, or preferred dysplasia-detection tool. This review outlines the available endoscopic technologies for the detection of dysplasia in IBD, considers the evidence supporting their use, and assesses which modalities are ready for use in clinical practice.
患有长期炎症性肠病（IBD）的患者患结直肠癌的风险增加。进行定期的发育异常筛查和监测可能会降低这种风险。迄今为止，染色内镜检查是唯一在大型、设计良好的发育异常检测试验中始终产生阳性结果的技术。大多数主要学会指南认可染色内镜检查作为辅助、可接受或首选的发育异常检测工具。本综述概述了用于检测IBD中发育异常的现有内镜技术，考虑了支持其使用的证据，并评估了哪些方法已准备好在临床实践中使用。
