Nguyen Thuc-Uyen, Pierce Mark C, Higgins Laura, Tkaczyk Tomasz S
Department of Bioengineering, Rice University, Houston, Texas 77030, USA.
Opt Express. 2013 Jun 3;21(11):13758-72. doi: 10.1364/OE.21.013758.
A snapshot 3-Dimensional Optical Coherence Tomography system was developed using Image Mapping Spectrometry. This system can give depth information (Z) at different spatial positions (XY) within one camera integration time to potentially reduce motion artifact and enhance throughput. The current (x,y,λ) datacube of (85×356×117) provides a 3D visualization of sample with 400 μm depth and 13.4 μm in transverse resolution. Axial resolution of 16.0 μm can also be achieved in this proof-of-concept system. We present an analysis of the theoretical constraints which will guide development of future systems with increased imaging depth and improved axial and lateral resolutions.
利用图像映射光谱技术开发了一种快照三维光学相干断层扫描系统。该系统能够在一次相机积分时间内给出不同空间位置（XY）处的深度信息（Z），从而有可能减少运动伪影并提高通量。当前（85×356×117）的（x，y，λ）数据立方体提供了深度为400μm、横向分辨率为13.4μm的样品的三维可视化。在这个概念验证系统中还可以实现16.0μm的轴向分辨率。我们对理论约束进行了分析，这将指导未来具有更高成像深度以及改进的轴向和横向分辨率的系统的开发。
