Carlsson Lotta Höglund, Norrelgen Fritjof, Kjellmer Liselotte, Westerlund Joakim, Gillberg Christopher, Fernell Elisabeth
Gillberg Neuropsychiatry Centre, Sahlgrenska Academy, Gothenburg University, Gothenburg, Sweden.
ScientificWorldJournal. 2013 Apr 23;2013:213979. doi: 10.1155/2013/213979. Print 2013.
To analyze cooccurring disorders and problems in a representative group of 198 preschool children with autism spectrum disorders (ASD) who had had interventions at a specialized habilitation center.
Parents and children were seen by a research team. Data were based on parental interviews, pediatric assessments, and tests of the child. Information on autistic symptoms, general cognitive function, speech and language, motor function, epilepsy, vision, hearing, activity level, behavior, and sleep was collected.
Three ASD categories were used: (1) autistic disorder (AD), (2) autistic-like condition (ALC) or Asperger syndrome, and (3) one group with autistic symptoms/traits but not entirely all its criteria met for ASD. Children with autism had a mean of 3.2 coexisting disorders or problems, the ALC/Asperger group had a mean of 1.6, and children with autistic traits had a mean of 1.6. The most common disorder/problems in the total group pertained to language problems (78%), intellectual disability (ID) (49%), below average motor function (37%), and severe hyperactivity/ADHD (33%).
The results accord with the concept of early symptomatic syndromes eliciting neurodevelopmental clinical examination (ESSENCE), and highlight the need of considering ASD in a broad perspective taking also other cooccurring developmental disorders into account.
分析198名在专门的 habilitation 中心接受过干预的自闭症谱系障碍(ASD)学龄前儿童的共病情况和问题。
一个研究团队对家长和孩子进行了观察。数据基于家长访谈、儿科评估以及对孩子的测试。收集了有关自闭症症状、一般认知功能、言语和语言、运动功能、癫痫、视力、听力、活动水平、行为和睡眠的信息。
使用了三种ASD类别:(1)自闭症障碍(AD),(2)自闭症样状况(ALC)或阿斯伯格综合征,以及(3)一组有自闭症症状/特征但不完全符合ASD所有标准的儿童。自闭症儿童平均有3.2种共存的疾病或问题,ALC/阿斯伯格组平均有1.6种,有自闭症特征的儿童平均有1.6种。整个群体中最常见的疾病/问题涉及语言问题(78%)、智力残疾(ID)(49%)、运动功能低于平均水平(37%)以及严重多动/注意力缺陷多动障碍(ADHD)(33%)。
结果符合早期症状综合征引发神经发育临床检查(ESSENCE)的概念,并强调需要从广泛的角度考虑ASD,同时也要考虑其他共存的发育障碍。