Nano-Primo Research Center, Advanced Institutes of Convergence Technology, Seoul National University, Suwon 443-270, Republic of Korea.
Evid Based Complement Alternat Med. 2013;2013:949245. doi: 10.1155/2013/949245. Epub 2013 May 12.
A primo vessel was observed in the abdominal cavity in the lung cancer mouse model, and its function as an extra metastatic path was observed. In this work, we found a primo vessel accompanying a blood vessel emanating from a tumor in the skin. We also presented simple and efficient criteria to distinguish a primo vessel from a blood or a lymph vessel and from a nerve. The criteria for using DAPI and Phalloidin will be useful in clinical situations to find and identify the primo vessels among the blood vessels, lymph vessels, or nerves in the tissue surrounding a tumor such as a melanoma or breast cancer.
在肺癌小鼠模型中观察到了初级脉管系统，并且观察到了它作为额外转移途径的功能。在这项工作中，我们发现了一种初级脉管系统，它伴随着从皮肤肿瘤中发出的血管。我们还提出了简单而有效的标准，以将初级脉管系统与血管、淋巴管或神经区分开来。使用 DAPI 和鬼笔环肽的标准将有助于在临床情况下在肿瘤（如黑色素瘤或乳腺癌）周围组织的血管、淋巴管或神经中找到并识别初级脉管系统。
